Controversial Issues in Deep Brain Stimulation in Parkinson's Disease

Chen, Shin-Yuan; Tsai, Shen Kou; Lin, Sheng-Di

doi:10.5772/16705

Cited by 2 publications

(3 citation statements)

References 70 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…the familiarity of the surgeon with the technique to be employed. 9 Cranial NMRI is one of the most used modalities for the location of the STN, which may be associated or not with skull tomography or ventriculography. Some of the advantages of the cranial NMRI are that it enables a better demarcation of the basal nuclei, a better visualization of critical structures for the prevention of injuries that may be inadvertently caused, and a clear demarcation of the electrode's trajectory.…”

Section: Resultsmentioning

confidence: 99%

“…The disadvantage of the magnetic field is nonlinear distortion, especially in the anteroposterior and medial-lateral axes. 4,9 The strategies to locate the dorsolateral portion of the STN can be classified as direct and indirect. The first is the direct visualization of the nucleus in the cranial NMRI images, whereas the second one uses fixed distances or the midpoint of the line between the anterior commissure (AC) and the posterior commissure (PC).…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Landmarks for the Location of the Subthalamic Nucleus Using Magnetic Resonance Imaging

Normanha

Leão

Silva

2017

Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery

View full text Add to dashboard Cite

► doença de Parkinson ► estimulação cerebral profunda ► núcleo subtalâmico ► pontos de referência anatômicos ResumoA estimulação cerebral profunda surgiu como opção terapêutica para a doença de Parkinson avançada na década de 1990, mas os primeiros relatos são do grupo de Benabid, neurocirurgião francês, na década de 1980. O núcleo subtalâmico (NST), mais especificamente sua porção dorsolateral, é o alvo mais comumente abordado. Um dos fatores primordiais para o bom resultado cirúrgico é a acurada localização desse alvo. Assim, este artigo teve como objetivo identificar landmarks que facilitem e refinem a localização do NST por ressonância nuclear magnética (RNM) de crânio. Para isso, foi realizada busca de artigos nas bases de dados PubMed e Science Direct, incluindo-se estudos sobre o uso da RNM de crânio para localização do NST. A localização precisa da porção dorsolateral do NST é de fundamental importância para se atingir a melhor resposta clínica sobre os sintomas motores da doença e minimizar os efeitos colaterais. A RNM de crânio é uma das modalidades localizatórias mais utilizadas, podendo ser associada ou não à tomografia de crânio ou à ventriculografia. As estratégias de localização podem ser classificadas em direta e indireta. Os landmarks estão entre as estratégias indiretas de visualização e os principais (núcleo rubro, sinal de Sukeroku, sinal do entalhe da cápsula interna, comissura supramamilar, trato mamilo talâmico e cisterna interpeduncular) são descritos neste artigo. Os diversos landmarks podem ser utilizados de forma integrada para obter localização mais refinada da porção dorsolateral do NST e o posicionamento ideal dos eletrodos para atingir melhor resposta clínica. AbstractDeep brain stimulation has become an option for the treatment of advanced Parkinson's disease since the 1990s, but the first reports are from Benabid's team, a French neurosurgeon, in the 1980s. The subthalamic nucleus (STN), more specifically its dorsolateral portion, is the most commonly stimulated brain area. One of the major aspects for a good surgical result is the accurate localization of this target. Therefore, this article aimed to identify landmarks that facilitate and refine the localization of STN using head magnetic resonance imaging (MRI). To achieve this goal, a research of

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Landmarks for the Location of the Subthalamic Nucleus Using Magnetic Resonance Imaging

Normanha

Leão

Silva

2017

Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery

View full text Add to dashboard Cite

show abstract

“…Volume estimates are commonly used as an index of scan quality, and have shown consistent deviations of more than 50% from ground truths when slice thicknesses were three times the size of the alternate planes [166]. Moreover, anisotropic voxels will decrease the accuracy of resampling to super resolutions, which is an automatically incorporated step of pre-operative planning systems [167]. The effects of voxel geometry on the visualization of subcortical structures (adapted from [164]).…”

Section: Voxel Sizesmentioning

confidence: 99%

Methodological Considerations for Neuroimaging in Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson’s Disease Patients

Isaacs

Keuken

Alkemade

et al. 2020

JCM

View full text Add to dashboard Cite

Deep brain stimulation (DBS) of the subthalamic nucleus is a neurosurgical intervention for Parkinson’s disease patients who no longer appropriately respond to drug treatments. A small fraction of patients will fail to respond to DBS, develop psychiatric and cognitive side-effects, or incur surgery-related complications such as infections and hemorrhagic events. In these cases, DBS may require recalibration, reimplantation, or removal. These negative responses to treatment can partly be attributed to suboptimal pre-operative planning procedures via direct targeting through low-field and low-resolution magnetic resonance imaging (MRI). One solution for increasing the success and efficacy of DBS is to optimize preoperative planning procedures via sophisticated neuroimaging techniques such as high-resolution MRI and higher field strengths to improve visualization of DBS targets and vasculature. We discuss targeting approaches, MRI acquisition, parameters, and post-acquisition analyses. Additionally, we highlight a number of approaches including the use of ultra-high field (UHF) MRI to overcome limitations of standard settings. There is a trade-off between spatial resolution, motion artifacts, and acquisition time, which could potentially be dissolved through the use of UHF-MRI. Image registration, correction, and post-processing techniques may require combined expertise of traditional radiologists, clinicians, and fundamental researchers. The optimization of pre-operative planning with MRI can therefore be best achieved through direct collaboration between researchers and clinicians.

show abstract

Controversial Issues in Deep Brain Stimulation in Parkinson's Disease

Cited by 2 publications

References 70 publications

Landmarks for the Location of the Subthalamic Nucleus Using Magnetic Resonance Imaging

Landmarks for the Location of the Subthalamic Nucleus Using Magnetic Resonance Imaging

Methodological Considerations for Neuroimaging in Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson’s Disease Patients

Contact Info

Product

Resources

About