“…[13][14][15] In addition, supramolecular polymers can be used as modular templates for the assembly of various biomolecules, including nanoparticles, 16,17 nucleic acids, 18,19 and proteins. [20][21][22][23] Recent work has revealed that intracellular signalling pathways heavily rely on the dynamic assembly of higher-order fibril-like aggregates that are structurally well-defined but open-ended and sometimes quasi-infinite. 24,25 As such, these assemblies function as platforms for the transient recruitment of signalling proteins that undergo proximity-induced activation, 26,27 and subsequently elicit immune or inflammatory responses, or apoptosis.…”