Controlled synthesis of water-dispersible conjugated polymeric nanoparticles for cellular imaging

Wang, Lili; Zhao, Peng; Feng, Chuying; Wu, Yusen; Ding, Yun; Hu, Aiguo

doi:10.1016/j.eurpolymj.2018.05.008

Cited by 4 publications

(2 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hyperbranched SCPNs have been synthesized through a variety of strategies including miniemulsion system and confined polymerization in nanoreactors. − Herein, a novel double-monomer (A 2 + B 4 ) methodology , was utilized to synthesize two series of donor–acceptor (D–A) type hyperbranched SCPNs (Scheme ) through direct (thiophene) arylation polycondensation reaction. The polycondensation reaction was well controlled by the in situ generation of AB 3 intermediates followed by polymerization in a hyperbranching manner.…”

mentioning

confidence: 99%

Hyperbranched Conjugated Polymer Dots: The Enhanced Photocatalytic Activity for Visible Light-Driven Hydrogen Production

Zhao

Wang

et al. 2019

Macromolecules

Self Cite

View full text Add to dashboard Cite

Conjugated polymer (CP) aggregates with linear/cross-linked structures are widely reported as photocatalysts for hydrogen evolution reaction. For full disclosure of the relationship between the photocatalytic performance and structural features of the CP photocatalysts, homogeneous dispersion of these CPs in aqueous medium is necessary, which however is difficult to be achieved. Herein, we report several coassembled polymeric dots (Pdots) consisting of PEG 45 -b-PMMA 103 and CPs with various structural features. We found that the Pdots of hyperbranched soluble CP nanoparticles (SCPNs) exhibit a high H 2 evolution rate up to 840 μmol h −1 g −1 with no platinum or rhodium as a cocatalyst, superior to their analogues with the linear or cross-linked structure. A possible charge-transfer mechanism suggests that the photoelectrons directly mobilize to the surface of these single-particulate Pdots over three-dimensional skeleton and successfully avoid the ineffective intermolecular charge transfer, leading to the shortened diffusion path of photoelectrons and enhanced photolysis efficacy. We believe that the high dispersion stability (2 months), solution processability, and structural tunability of these Pdots with hyperbranched SCPNs would inspire further research on designing multicomponent photocatalysts for highly efficient visible light-driven hydrogen evolution reaction.

show abstract

mentioning

confidence: 99%

Hyperbranched Conjugated Polymer Dots: The Enhanced Photocatalytic Activity for Visible Light-Driven Hydrogen Production

Zhao

Wang

et al. 2019

Macromolecules

Self Cite

View full text Add to dashboard Cite

show abstract

“…Polymeric nanoparticles provide a broad range of applications in the biomedical field as they generally provide a synthetic platform offering high capacity for chemical modifications as well as control over their relative sizes. 1 Based on their ease of synthesis and the opportunities to impart multiple functionalities toward biological targets of interest, polymeric nanoparticles have emerged as versatile tools for cellular imaging 2,3 as well as for delivery applications. 4,5 However, to further increase their acceptance for biomedical usage, the design and synthesis of new materials providing control over very small particle sizes that reveal high tissue penetration, while maintaining biocompatibility and high colloidal stability, are highly favorable.…”

Section: Introductionmentioning

confidence: 99%

Facile synthesis of ultrasmall polydopamine-polyethylene glycol nanoparticles for cellular delivery

Harvey

Szelwicka

et al. 2018

Biointerphases

View full text Add to dashboard Cite

Very small polydopamine (PDA) polyethylene glycol (PEG) crosslinked copolymer (PDA-PEG) nanoparticles have been prepared following a convenient one-step procedure in aqueous solution. Particle sizes and colloidal stabilities have been optimized by varying PEG in view of chain length and end group functionalities. In particular, amine-terminated PEG3000 [PEG 3000 (NH 2) 2 ] reacted with polydopamine intermediates so that very small, crosslinked PDA-PEG nanoparticles with sizes of less than 50 nm were formed. These nanoparticles remained stable in buffer solution and no sedimentation occurred. Chemical functionalization was straightforward as demonstrated by the attachment of fluorescent dyes. The PDA-PEG nanoparticles revealed efficient cellular uptake via endocytosis and high cytocompatibility, thus rendering them attractive candidates for cell imaging or for drug delivery applications.

show abstract

Narrowly Distributed Conjugated Polymers Synthesized Through Acid‐Catalyzed Aldol Polycondensations in Nanoreactors

Shi,

Huang,

Tian

et al. 2024

Macro Chemistry & Physics

View full text Add to dashboard Cite

Conjugated polymers are typically synthesized through transition metal‐mediated coupling reactions, which are often costly and have significant environmental impacts. Aldol condensation represents a more cost‐effective and sustainable synthetic technique for developing next‐generation organic functional materials. However, controlling the molecular weight and distribution of the resulting polymers remains challenging due to the uncontrollable step‐growth polymerization mechanism of aldol polycondensations. To this end, by selectively anchoring sulfonic acids inside the mesochannels of SBA‐15, the aldol polycondensation is exclusively confined within the pores. Experimental results demonstrate that this nanoreactor, by providing a spatially confined reaction environment, aids in controlling the progression of the polymerization and the growth of polymer chains, thereby achieving good control over polymer molecular weight and distribution, giving linear conjugated polymers and soluble conjugated polymeric nanoparticles with polymer dispersity down to 1.31.

show abstract

Controlled synthesis of water-dispersible conjugated polymeric nanoparticles for cellular imaging

Cited by 4 publications

References 44 publications

Hyperbranched Conjugated Polymer Dots: The Enhanced Photocatalytic Activity for Visible Light-Driven Hydrogen Production

Hyperbranched Conjugated Polymer Dots: The Enhanced Photocatalytic Activity for Visible Light-Driven Hydrogen Production

Facile synthesis of ultrasmall polydopamine-polyethylene glycol nanoparticles for cellular delivery

Narrowly Distributed Conjugated Polymers Synthesized Through Acid‐Catalyzed Aldol Polycondensations in Nanoreactors

Contact Info

Product

Resources

About