Controlled manipulation of Fe<sub>3</sub>O<sub>4</sub>nanoparticles in an oscillating magnetic field for fast ablation of microchannel occlusion

Gabayno, Jacque Lynn; Liu, Dawei; Chang, Ming; Lin, Yu-Hao

doi:10.1039/c4nr06143h

Cited by 31 publications

(31 citation statements)

References 40 publications

(38 reference statements)

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“…The linear translation of the NPs along the microchannel responds to a magnetic force ( F x ) given by [7]:

\overset{F_{x}}{true} = μ_{0} χ H_{y} V \cdot \frac{\partial {\vec{H}}_{y}}{\partial x}

where μ 0 is the vacuum permeability, χ is the material susceptibility, V is the volume of the surface-coated NPs, H y is the magnetic field strength, and

\frac{\partial {\vec{H}}_{y}}{\partial x}

is the gradient field.…”

Section: Magnetically Controlled Motion Of Nanoparticlesmentioning

confidence: 99%

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Magnetic Control of Fe3O4 Nanomaterial for Fat Ablation in Microchannel

Chang

Lin

et al. 2015

Materials

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In this study, surface modification of iron (II, III) oxide Fe3O4 nanoparticles by oleic acid (OA) coating is investigated for the microablation of fat in a microchannel. The nanoparticles are synthesized by the co-precipitation method and then dispersed in organic solvent prior to mixing with the OA. The magnetization, agglomeration, and particle size distribution properties of the OA-coated Fe3O4 nanoparticles are characterized. The surface modification of the Fe3O4 nanoparticles reveals that upon injection into a microchannel, the lipophilicity of the OA coating influences the movement of the nanoparticles across an oil-phase barrier. The motion of the nanoparticles is controlled using an AC magnetic field to induce magnetic torque and a static gradient field to control linear translation. The fat microablation process in a microchannel is demonstrated using an oscillating driving field of less than 1200 Am−1.

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“…The linear translation of the NPs along the microchannel responds to a magnetic force ( F x ) given by [7]:

\overset{F_{x}}{true} = μ_{0} χ H_{y} V \cdot \frac{\partial {\vec{H}}_{y}}{\partial x}

where μ 0 is the vacuum permeability, χ is the material susceptibility, V is the volume of the surface-coated NPs, H y is the magnetic field strength, and

\frac{\partial {\vec{H}}_{y}}{\partial x}

is the gradient field.…”

Section: Magnetically Controlled Motion Of Nanoparticlesmentioning

confidence: 99%

“…Bare magnetic Fe 3 O 4 NPs in suspension can be controlled to move in a low gradient and oscillating magnetic fields [7]. A velocity field created by the movement of the NPs was necessary to facilitate the microablation of a thrombus in a microchannel.…”

Section: Introductionmentioning

confidence: 99%

Magnetic Control of Fe3O4 Nanomaterial for Fat Ablation in Microchannel

Chang

Lin

et al. 2015

Materials

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“…The magnitude of the magnetic torque needed to rotate the NPs can be calculated by Equation (1) where V is the volume of the NPs, χ is the material susceptibility, μ 0 is the vacuum permeability, H is the magnetic field strength, and θ is the angle between the magnetic dipole moment of the NPs and H [15].

τ_{m} = V \frac{χ^{2}}{2 (2 + sans-serifχ)} μ_{0} H^{2} \sin (2 sans-serifθ)

…”

Section: Methodsmentioning

confidence: 99%

Antibacterial Effects of Magnetically-Controlled Ag/Fe3O4 Nanoparticles

et al. 2018

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This paper presents the use of a magnetic manipulation device to remotely control the movement of Ag/Fe3O4 nanoparticles (NPs) for enhancing the antibacterial effect of Ag particles in aqueous suspensions containing Escherichia coli (E. coli). The Ag/Fe3O4 magnetic NPs were prepared by co-precipitation method where the Ag particles are simultaneously synthesized with the Fe3O4 particles to form Ag and Fe3O4 nanocomposite materials. The manipulation system utilized a homogeneous rotating magnetic field to carry out magnetic stirring of NPs in the petri dishes containing bacterial suspensions. The optimum magnetron parameters and best antibacterial effects were implemented with six different concentrations from 0.6 wt % to 6.6 wt % of the NPs at driving frequencies from 50 rpm to 200 rpm for 3 min. The highest antibacterial effect of 99.4% was achieved at 5.4 wt % of NPs and the driving frequency of 100 rpm. A time-dependent antibacterial effect in 0.1 wt % of Ag/Fe3O4 was also observed. The results indicate that the use of specific rotating magnetic fields to manipulate Ag/Fe3O4 magnetic NPs can significantly improve the antibacterial efficacy. Due to the good biocompatibility of the Ag NPs, the presented technique can be applied to clean water resources in the future.

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“…For a magnetic aggregate placed in a magnetic field H, the driving magnetic torque is (16) where V = 4πab 2 /3 is the volume of the magnetic aggregate and χ is magnetic susceptibility.…”

Section: Principle Of Softening Stoolmentioning

confidence: 99%

“…Zhou and Metin (15) proposed an approach for the fluidic trapping and two-dimensional transport of swimming microorganisms, which utilizes a rotating magnetic microrobot. Gabayno et al (16,17) developed thrombolysis technology, in which a strong vortex is induced by rotating magnetic aggregates for breaking a thrombus. These experiments indicate that micro-and nanomaterials can impact the target indirectly with the help of a rotational fluid induced by fast rotating micro-or nanomaterials.…”

Section: Introductionmentioning

confidence: 99%

Softening Hard Stool Using Magnetically Controlled Fe3O4 Nanoparticles

2017

Sensors and Materials

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Fecal impaction is a gastrointestinal problem that occurs in all age groups. Traditional therapy with drugs or surgery may result in serious complications for patients. Softening hard stool in vitro is realized with swaying Fe 3 O 4 nanoparticle (NP) aggregates controlled by an oscillating magnetic field generated using a combination of electromagnetic coils and permanent magnets. The operation mechanism of the combined oscillating magnetic field is analyzed, experiments on NP manipulation by the magnetic field are conducted, and the morphology and sway motion characteristics of the aggregates are observed under various experimental parameter settings. Experimental results show that such NP aggregates manipulated by oscillating magnetic fields can be applied to soften stool in the rectum for fecal impaction treatment. In addition, diagnosis and sensing of constipation induced by obstruction in the gastrointestinal tract can be executed by the same approach in the future.

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Controlled manipulation of Fe₃O₄nanoparticles in an oscillating magnetic field for fast ablation of microchannel occlusion

Cited by 31 publications

References 40 publications

Magnetic Control of Fe3O4 Nanomaterial for Fat Ablation in Microchannel

Magnetic Control of Fe3O4 Nanomaterial for Fat Ablation in Microchannel

Antibacterial Effects of Magnetically-Controlled Ag/Fe3O4 Nanoparticles

Softening Hard Stool Using Magnetically Controlled Fe3O4 Nanoparticles

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Controlled manipulation of Fe3O4nanoparticles in an oscillating magnetic field for fast ablation of microchannel occlusion

Cited by 31 publications

References 40 publications

Magnetic Control of Fe3O4 Nanomaterial for Fat Ablation in Microchannel

Magnetic Control of Fe3O4 Nanomaterial for Fat Ablation in Microchannel

Antibacterial Effects of Magnetically-Controlled Ag/Fe3O4 Nanoparticles

Softening Hard Stool Using Magnetically Controlled Fe3O4 Nanoparticles

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Product

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Controlled manipulation of Fe₃O₄nanoparticles in an oscillating magnetic field for fast ablation of microchannel occlusion