Controlled iodine release from polyurethane sponges for water decontamination

Aviv, Oren; Laout, Natalia; Ratner, S. B.; Harik, Oshrat; Kunduru, Konda Reddy; Domb, Abraham J.

doi:10.1016/j.jconrel.2013.09.018

Cited by 13 publications

(7 citation statements)

References 11 publications

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“…Iodine is one of the most effective antiseptics, commonly used as an antimicrobial agent as it has bactericidal, fungicidal and viricidal properties (2). It has been used for the prevention or management of wound infections for over 150 years.…”

mentioning

confidence: 99%

Quantitative analysis of povidone-iodine thin films by X-ray photoelectron spectroscopy and their physicochemical properties

Sa¹,

Sawatdee²,

Phadoongsombut

et al. 2017

Acta Pharmaceutica

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In this study, povidone-iodine (PVP-I) has been formulated as a topical spray to produce a thin film for the controlled release of I 2 . By means of experimental design, 27 formulations containing glycerol, ethanol, PEG 400, copovidone and HFA 134a as a propellant were prepared. The pH values of all formulations were in the range of 6-7. The viscosity was within the range of 11.9-85.9 mPa s. The surface tensions were 20.3 to 24.6 mN m -1 and the contact angles were between 19.3 and 38.7°. The assays for the iodine contents were within acceptable range (80-120 %). X-ray photoelectron spectroscopy analysis revealed the ionized form of iodine was much higher than the unionized form. The MIC and MBC values of the PVP-I sprays against Staphylococcus aureus, S. epidermidis and Pseudomonas aeruginosa were higher than that of commercial PVP-I solution. The cytotoxicity study confirmed that the PVP-I spray had lower toxic effects on keratinocytes and fibroblasts compared to the commercial PVP-I solution. The formulation containing 59 % ethanol, 18 % copovidone and 12 % PEG 400 showed good antibacterial activity.Keywords: povidone-iodine, topical spray, bioactivity, cytotoxicity, X-ray photoelectron spectroscopy Human skin harbors many kinds of bacteria, including potential pathogenic bacteria such as Staphylococcus aureus, Streptococcus pyogenes, S. epidermidis, Pseudomonas aeruginosa and even some anaerobic bacteria such as Clostridium spp. that could induce tetanus. These microbes can initiate diseases such as gangrene and dermatitis, when the skin is damaged (1). At procedural and surgical sites, bacteria can create infections that lead to complex

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mentioning

confidence: 99%

Quantitative analysis of povidone-iodine thin films by X-ray photoelectron spectroscopy and their physicochemical properties

Sa¹,

Sawatdee²,

Phadoongsombut

et al. 2017

Acta Pharmaceutica

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“…Recent scientific research on water treatment has yielded various antibacterial materials to improve water quality. Table compares some typical antibacterial materials for water treatment via different modes. − In terms of efficiency of bacterial decontamination, the P(St-DVB-NVP)-I 2 designed herein seems to have comparable or even better capability against aquatic bacteria. On the basis of its excellent antibacterial activity and good biocompatibility, we tested the effectiveness of P(St-DVB-NVP)-I 2 for water bacterial decontamination.…”

Section: Resultsmentioning

confidence: 99%

Antibacterial Povidone-Iodine-Conjugated Cross-Linked Polystyrene Resin for Water Bacterial Decontamination

Gao¹,

Borjihan²,

Yang

et al. 2019

ACS Appl. Bio Mater.

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Bacterial contamination in water purification systems is generating significant concern as a global health issue. In this paper, we describe fabricating antibacterial povidone-iodine-conjugated cross-linked polystyrene resins (i.e., P(St-DVB-NVP)-I2) and investigating them as antimicrobial agents for water decontamination. Comprehensive antibacterial tests showed that the addition of povidone-iodine to polystyrene resins resulted in strong antibacterial activity against pathogenic bacteria. In addition, the as-synthesized P(St-DVB-NVP)-I2 was confirmed to have hydrophobicity and favorable biocompatibility. We then examined the possibility of using P(St-DVB-NVP)-I2 as an antibacterial filter for water treatment and found that it could efficiently remove bacteria from water. An analog experiment demonstrated that the capability of P(St-DVB-NVP)-I2 for water bacterial decontamination was not influenced by the presence of mineral ions in the water. Most significantly, we confirmed the potential reusability of P(St-DVB-NVP)-I2 through a recycling test. This method of creating an antibacterial resin by building a conjugation of cross-linked polystyrene with povidone-iodine is safe, cost-effective, and environmentally friendly, and the resin shows promise for use in water purification filters.

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“…The cross-sectional SEM images confirm that ELV-WP-FG aggregation might be occurring during the foaming process, since larger particles are observed in 0.1% ELV-WP-FG-PUF. The surface morphology of the PUF can depend on the blowing agent used, along with the properties of the polyol used [51][52][53] .…”

Section: Resultsmentioning

confidence: 99%

Upcycling end-of-life vehicle waste plastic into flash graphene

et al. 2022

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Responsible disposal of vehicles at the end of life is a pressing environmental concern. In particular, waste plastic forms the largest proportion of non-recycled waste material from light-duty vehicles, and often ends up in a landfill. Here we report the upcycling of depolluted, dismantled and shredded end-of-life waste plastic into flash graphene using flash Joule heating. The synthetic process requires no separation or sorting of plastics and uses no solvents or water. We demonstrate the practical value of the graphene as a re-inforcing agent in automotive polyurethane foam composite, where its introduction leads to improved tensile strength and low frequency noise absorption properties. We demonstrate process continuity by upcycling the resulting foam composite back into equal-quality flash graphene. A prospective cradle-to-gate life cycle assessment suggests that our method may afford lower cumulative energy demand and water use, and a decrease in global warming potential compared to traditional graphene synthesis methods.

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Controlled iodine release from polyurethane sponges for water decontamination

Cited by 13 publications

References 11 publications

Quantitative analysis of povidone-iodine thin films by X-ray photoelectron spectroscopy and their physicochemical properties

Quantitative analysis of povidone-iodine thin films by X-ray photoelectron spectroscopy and their physicochemical properties

Antibacterial Povidone-Iodine-Conjugated Cross-Linked Polystyrene Resin for Water Bacterial Decontamination

Upcycling end-of-life vehicle waste plastic into flash graphene

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