Controlled drug release using nanoporous anodic aluminum oxide on stent

Kang, Ho-Jae; Kim, Deug Joong; Park, Sung‐Joon; Yoo, Ji‐Beom; Ryu, Yunha

doi:10.1016/j.tsf.2006.10.029

Cited by 64 publications

(33 citation statements)

References 7 publications

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“…It is most likely that difficulties with control of loading and release of drug from the nanometer-sized pores (5-15 nm) is a significant challenge due to their small size. In a fundamental drug-loading and drug-release study of such structures it has been shown that uncontrolled release occurs when drug adhered to the outer surface rather than being deposited within the pores [66].…”

Section: Nanoporous Aluminium Oxidementioning

confidence: 99%

The evolution of cardiovascular stent materials and surfaces in response to clinical drivers: A review

2009

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Section: Nanoporous Aluminium Oxidementioning

confidence: 99%

The evolution of cardiovascular stent materials and surfaces in response to clinical drivers: A review

2009

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“…As expected, drugs are not exclusively loaded inside the pores of PAA, but the surface itself can also withhold a part of this load, that can be considerably high, promoting a different stage release [46]. Generally, thermogravimetric analysis is used for determining the quantity of drug loaded on porous platforms [47,48].…”

Section: Drug Deliverymentioning

confidence: 84%

Mesoporous alumina as a biomaterial for biomedical applications

Xifré-Pérez

Ferre-Borull

Pallarès

et al. 2015

Open Material Sciences

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Porous anodic alumina (PAA) is a biomaterial based on a cost-effective electrochemical anodization of pure aluminum with unique geometrical properties, i.e., self-ordering hexagonal pore distribution, tunable pore diameters and interpore distances, and uniformity of the pores in the vertical direction (nanochannels). These remarkable properties have found important applications in several fields such as energy storage, optics, photonics, magnetism, catalysis and, in particular, in the biomedicine field. In this work, we review the current state of research and key issues on cell culture and implants, drug delivery systems with complex release profiles and specific action, and high efficiency and sensitivity biosensors with different biosensing mechanisms, all of them based on PAA. The biocompatibility, morphology of the surface, nanoestructural engineering in-depth, surface functionalization and coatings are discussed and analyzed in detail.

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“…Porous anodized alumina (PAA) is one of the most exciting nanostructured material which has gained significant attention for applications in gas separation [1], drug delivery [2], bone fixation [3], and a template for nanostructures formation [4,5]. PAA membrane consists of an ordered hexagonal arrangement of cells with a central pore per cell that elongates from top to bottom of the layer, resembling a honeycomb network [6,7].…”

Section: Introductionmentioning

confidence: 99%

Formation of self-ordered porous anodized alumina template for growing tungsten trioxide nanowires

et al. 2014

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Uniform porous anodized aluminum oxide (AAO) membrane has been synthesized by two-step anodization for fabricating tungsten trioxide (WO 3 ) nanowires. Under assayed conditions, uniform porous structure of alumina (Al 2 O 3 ) membrane with long range ordered hexagonal arrangements of nanopores was achieved. The self-assembled template possesses pores of internal diameter of 50 nm and interpore distance (d int ) of 80 nm with a thickness of about 80 lm, i.e., used for fabrication of nanostructures. WO 3 nanowires have been fabricated by simple electroless deposition method inside Al 2 O 3 nanopores. SEM images show tungsten trioxide nanowire with internal diameter of about 50 nm, similar to porous diameter of AAO template. XRD results showed that nanowires exist in cubic crystalline state with minor proportion of monoclinic phase.

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Controlled drug release using nanoporous anodic aluminum oxide on stent

Cited by 64 publications

References 7 publications

The evolution of cardiovascular stent materials and surfaces in response to clinical drivers: A review

The evolution of cardiovascular stent materials and surfaces in response to clinical drivers: A review

Mesoporous alumina as a biomaterial for biomedical applications

Formation of self-ordered porous anodized alumina template for growing tungsten trioxide nanowires

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