2021
DOI: 10.1088/1748-605x/ac0087
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Controllable performance of a dopamine-modified silk fibroin-based bio-adhesive by doping metal ions

Abstract: Bio-adhesives are essential for wound healing because of their convenience and safety. Although widely used as biomaterials, silk fibroin’s (SF’s) further application as bio-adhesive is hindered due to its weak stickiness with tissue and slow gelation speed. Here, a dopamine-modified SF-based bio-adhesive is fabricated by using genipin as the chemical cross-linking agent. Furthermore, metal ions have been used to adjust the adhesion property of the bio-adhesive. The experimental results shows that the dopamine… Show more

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Cited by 12 publications
(4 citation statements)
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“…Drug delivery [136], tissue adhesion [137], tissue engineering [138], food packaging [139], electrochemistry [140],…”
Section: Applicationsmentioning
confidence: 99%
“…Drug delivery [136], tissue adhesion [137], tissue engineering [138], food packaging [139], electrochemistry [140],…”
Section: Applicationsmentioning
confidence: 99%
“…Yin et al fabricated a DOPA-modified silk fibroin-based bioadhesive and chemically cross linked the structure using genipin [ 51 ]. Furthermore, metal ions have also been utilized to modify the adhesion properties of adhesive (dopamine modified).…”
Section: Categories Of Tissue Adhesivesmentioning
confidence: 99%
“…This procedure can also be used for modification of substrate to increase its adhesion. For instance, Yin and colleagues used EDC-NHS reaction to incorporate dopamine hydrochloride into silk fibroin structure to promote its adhesion properties [ 51 ].…”
Section: Common Mechanisms Of Silk Fibroin Adhesionmentioning
confidence: 99%
“…Rumeysa Tutar et al (Tutar et al, 2022) synthesized a biocompatible and photocross-linked ocular tissue adhesive composite hydrogel from silk fibroin for corneal injury. Zichu Yin et al (Yin et al, 2021) prepared a dopamine-modified SF-based bioadhesive using genipin as a cross-linking agent.…”
Section: Silk Fibroinmentioning
confidence: 99%