Control of Grain Size and Weight by the OsMKKK10-OsMKK4-OsMAPK6 Signaling Pathway in Rice

Xu, Ran; Duan, Penggen; Yu, Haiyue; Zhou, Zhengkui; Zhang, Baolan; Wang, Ruci; Li, Jing; Zhang, Guozheng; Zhuang, Shangshang; Lyu, Jia; Li, Na; Chai, Tuanyao; Tian, Zhixi; Yao, Shanguo; Li, Yunhai

doi:10.1016/j.molp.2018.04.004

Cited by 182 publications

(145 citation statements)

References 59 publications

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“…A rice MAPK cascade (OsMKKK10‐OsMKK4‐OsMAPK6) has been shown to play critical roles in regulating grain size (Duan et al ; Liu et al ; Guo et al ; Xu et al , ). Currently, it is unclear whether this MAPK cascade acts downstream of G proteins to regulate rice grain size.…”

Section: The Effectors Of G Protein Signaling In Grain Size Controlmentioning

confidence: 99%

Control of grain size by G protein signaling in rice

2019

JIPB

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Heterotrimeric G proteins are involved in multiple cellular processes in eukaryotes by sensing and transducing various signals. G protein signaling in plants is quite different from that in animals, and the mechanisms of plant G protein signaling are still largely unknown. Several recent studies have provided new insights into the mechanisms of G protein signaling in rice grain size and yield control. In this review, we summarize recent advances on the function of G proteins in rice grain size control and discuss the potential genetic and molecular mechanisms of plant G protein signaling.

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Section: The Effectors Of G Protein Signaling In Grain Size Controlmentioning

confidence: 99%

Control of grain size by G protein signaling in rice

2019

JIPB

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“…In addition, OsMKK4 physically interacts with OsMAPK6 to form a regulatory module regulating rice grain size (Liu et al 2015b). Recently, it was reported that OsMKKK10 also functions in the regulation of grain size by interacting with and phosphorylating OsMKK4, establishing the OsMKKK10‐OsMKK4‐OsMAPK6 cascade controlling grain size and weight (Guo et al 2018; Xu et al 2018).…”

Section: Introductionmentioning

confidence: 99%

The rice PLATZ protein SHORT GRAIN6 determines grain size by regulating spikelet hull cell division

Zhou

Hou

2019

JIPB

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Grain size is a major determinant of cereal grain yields; however, the relevant regulatory mechanisms controlling this trait have not been fully elucidated. The rice (Oryza sativa) mutant short grain6 (sg6) was identified based on its reduced grain length and weight. Here, we functionally characterized the role of SG6 in determining grain size through the regulation of spikelet hull cell division. SG6 encodes a previously uncharacterized plant ATrich sequence and zinc-binding (PLATZ) protein that is ubiquitously localized throughout the cell and is preferentially expressed in the early developing panicles but not in the endosperm. The overexpression of SG6 resulted in significantly larger and heavier grains, as well as increased plant heights, which is consistent with its elevated spikelet hull cell division rate. Yeast two-hybrid analyses revealed that SG6 interacts with the core cell cycle machinery DP protein and several other putative cell division regulators, consistent with our transcriptomic analysis, which showed that SG6 activates the expression of many DNA replication and cell-cycle-related genes. These results confirm the crucial role of SG6 in determining grain size by regulating spikelet hull cell division and provide clues for understanding the functions of PLATZ family proteins and the network regulating cereal grain size.

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“…Several genes in different signaling pathways play roles in grain size determination (Li and Li ). For example, the mitogen‐activated protein kinase (MAPK) pathway controls grain size by affecting the number of spikelet hull cells (Duan et al ; Liu et al ; Guo et al ; Xu et al ). SMALL GRAIN 1 ( SMG1 ) encodes a MAPK kinase (OsMAPKK4) that regulates grain size by affecting cell proliferation (Duan et al ).…”

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GRAIN LENGTH AND AWN 1 negatively regulates grain size in rice

Wang

Zou

et al. 2019

JIPB

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Summary Grain size is an important factor determining yield in rice. Here, we identified a recessive mutant gene, grain length and awn 1 (gla1), which caused a significant increase in grain length and weight, and was associated with long awns. The gla1 mutation was mapped to a single‐nucleotide polymorphism in a gene encoding a cytoplasmically‐localized mitogen‐activated protein kinase (MAPK) phosphatase. Overexpression of GLA1 caused a decrease in grain length, and the GLA1 protein interacted with OsMAPK6. These results suggest that GLA1 may serve as a negative regulator of the OsMAPKK4‐OsMAPK6 cascade, controlling grain size via the dephosphorylation of OsMAPK6.

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Control of Grain Size and Weight by the OsMKKK10-OsMKK4-OsMAPK6 Signaling Pathway in Rice

Cited by 182 publications

References 59 publications

Control of grain size by G protein signaling in rice

Control of grain size by G protein signaling in rice

The rice PLATZ protein SHORT GRAIN6 determines grain size by regulating spikelet hull cell division

GRAIN LENGTH AND AWN 1 negatively regulates grain size in rice

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