The present research aims at comprehensive analysis to determine the effectiveness of cardiac surgery in patients in the acute period of myocardial infarction in comparison with patients who received drug treatment. A comparative assessment of the level of hospital mortality was carried out in the groups of patients of senior working age, elderly and old age, dividing them into patients who received cardiac surgery (main group) and drug treatment (comparison group). Among the patients of working age, 284 were assigned to the main group and 272 to the comparison group; among the patients of elderly age, 104 were assigned to the main group and 363 to the comparison group; and among the patients of old age, there were 9 patients in the main group and 235 patients in the comparison group. For reliable difference between the compared indicators, the authors determined the relative risk of socio-hygienic factors in terms of mortality rate and the significant limit of mortality formation, taking into account that the factor the relative risk of which is more than one is significant. The significant difference in mortality in hospital between patients who received high-tech medical services (HTMS) and the group of patients who did not undergo such high-tech heart surgery was found only in the elderly patients (65-74 years old), p = 0.002 (chi-square). The number of deaths in hospital from myocardial infarction in the main group increases with age. Mathematical modeling showed that the level of hospital mortality is also influenced by the provision of the hospital with qualified cardiologists, specialized bed and special medical equipment.