Contrast sensitivity function and pituitary adenoma: a study of 40 cases.

Grochowicki, M; Vighetto, Alain; Berquet, S; Sassolas, G

doi:10.1136/bjo.74.6.358

Cited by 8 publications

(3 citation statements)

References 3 publications

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“…In Grochowski's opinion, the examination of contrast sensitivity is a susceptible method for the determination of visual pathway compression. However, it should not be used separately from other examination methods of the visual system (18). Gutowski et al evaluated 11 patients who had tumors in the sella turcica and had no visual acuity and visual field impairment; however, color contrast sensitivity impairment was found (19).…”

Section: Resultsmentioning

confidence: 99%

Changes of Visual Functions in Patients With Pituitary Adenoma

et al. 2013

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Background and Objective. The aim of this study was to evaluate associations between visual functions (visual acuity, perimetry, optic nerve disc condition, and color contrast sensitivity) and pituitary adenoma (PA) diameter. Material and Methods. In the study, 20 patients with PA, which was confirmed by computed tomography or magnetic resonance imaging scans, were examined. The patients were divided into 2 groups: those with a PA diameter of ≤1 cm (14 eyes) and with a PA diameter of >1 cm (26 eyes). The control group comprised 40 healthy age- and gender-matched persons (80 eyes). The diameter of PA, visual acuity, and perimetry were analyzed; the F-M 100 hue test for color discrimination was used in patients with PA. Results. Visual acuity was better in the control group as compared with both groups of patients (1.0 vs. 0.90 [SD, 0.50] and 0.64 [SD, 0.21]; P=0.01; respectively). The results of the Farnsworth- Munsell 100 hue test were also better in the control group compared with the patients with PA of ≤1 cm and >1 cm (error score of 80.1 [SD, 53.0] vs. 131.8 [SD, 30.6] and 244.68 [SD, 51. 6], respectively; P=0.011). There was a very strong positive correlation between the error score of the F-M 100 hue test and PA diameter (r=0.905), but the correlation between the error score and visual acuity (r=–0.32), perimetry (r=0.21), and eye fundus changes (r=0.36) and PA diameter was weak. Conclusions. Our results showed that PA can cause the impairments of visual acuity, perimetry, and color contrast sensitivity. The computerized F-M 100 hue test can be one of the methods for an early diagnosis of chiasm damage in patients with PA.

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Section: Resultsmentioning

confidence: 99%

Changes of Visual Functions in Patients With Pituitary Adenoma

et al. 2013

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“…Researchers have determined great color contrast sensitivity impairment in patients diagnosed with PA [ 24 ]. In Grochowicki et al [ 25 ]'s opinion, the contrast sensitivity examination is a suitable method to determine visual pathway compression. However, it should not be used separately from other examination methods of the visual system.…”

Section: Discussionmentioning

confidence: 99%

The Application of a New Maximum Color Contrast Sensitivity Test to the Early Prediction of Chiasma Damage in Cases of Pituitary Adenoma: The Pilot Study

Slatkevičienė

Liutkevičienė

Glebauskiene

et al. 2016

Korean J Ophthalmol

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PurposeOur objective was to estimate the maximum color contrast sensitivity (MCCS) thresholds in individuals with chiasma opticum damage.MethodsThe pilot study tested 41 people with pituitary adenoma (PA) and 100 age- and gender-matched controls. Patients were divided into two groups according to PA size, PA ≤1 cm or PA >1 cm. A new MCCS test program was used for color discrimination.ResultsThe mean total error score (TES) of MCCS was 1.8 in the PA ≤1 cm group (standard deviation [SD], 0.38), 3.5 in the PA >1 cm group (SD, 0.96), and 1.4 in the control group (SD, 0.31; p < 0.001). There was a positive correlation between tumor size and MCCS result (r = 0.648, p < 0.01). In the group that had PA-producing hormones, the TES was 2.5 (SD, 1.09), compared to 4.2 value in the non-functioning PA group of patients that did not have clinically significant hormone excess (SD, 3.16; p < 0.01). In patients with normal visual acuity (VA) or visual field MCCS, the TES was 3.3 (SD, 1.8), while that in patients with VA <0.00 was 4.6 (SD, 2.9).ConclusionsResults of the MCCS test TES were 1.9 times better in patients with PA ≤1 cm compared to patients with PA >1 cm (p < 0.01). In PA patients with normal VA, the TES was 2.35 times worse than that of healthy persons (p < 0.01).

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“…Studies of temporal contrast sensitivity have shown both uniform and low temporal frequency loss of contrast sensitivity in patients with chiasmal compression 48. Studies assessing spatial frequency sensitivity in lesions affecting the suprasellar region have found alterations either to be total or limited to low to medium spatial frequencies only 49. A recent study of psychophysical losses in foveal sensitivity found significant losses in chromatic, luminance, and temporal sensitivities in patients with suprasellar lesions without field defects 50…”

Section: Visual Failurementioning

confidence: 99%