The Application of a New Maximum Color Contrast Sensitivity Test to the Early Prediction of Chiasma Damage in Cases of Pituitary Adenoma: The Pilot Study

Slatkevičienė, Girėna; Liutkevičienė, Rasa; Glebauskiene, Brigita; Žaliūnienė, Dalia; Kriauciuniene, Loresa; Bernotas, Giedrimantas; Tamašauskas, Arimantas

doi:10.3341/kjo.2016.30.4.295

Cited by 2 publications

(2 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some authors have described that color vision loss is strongly associated with VF defects due to chiasm compression ( Okamoto et al, 2010 ; Barzaghi et al, 2012 ; Yu et al, 2015 ; Sun et al, 2017 ). Slatkeviciene et al (2016) reported that contrast sensitivity is approximately 2.4 times lower in PMA subjects than in healthy individuals ( Slatkeviciene et al, 2016 ). In our study, BCVA, CV, CS 1m, and 3m were different between patients with PMA and healthy controls ( p < 0.001).…”

Section: Discussionmentioning

confidence: 99%

Bi-nasal sectors of ganglion cells complex and visual evoked potential amplitudes as biomarkers in pituitary macroadenoma management

Hernández-Echevarría¹,

Cuétara-Lugo²,

Pérez-Benítez³

et al. 2022

Front. Integr. Neurosci.

View full text Add to dashboard Cite

The study aimed to evaluate the retinal ganglion cell structure using optical coherence tomography and the visual pathway function employing visual evoked potentials in the diagnosis and monitoring of patients with pituitary macroadenoma. A descriptive, cross-sectional, and longitudinal study (3 and 12 months follow-up) was conducted on forty-two patients. Thirty-five age-matched healthy controls were used in the cross-sectional one. Full neuro-ophthalmological evaluation (structural and functional) was carried out including global and segmented retinal nerve fiber layer/ganglion cell complex analysis and amplitude and latency of P100 component in the electrophysiology. Statistical data analysis was conducted with R version 3.6.3 and Python version 3.8. Associations were evaluated using Spearman’s correlations. Amplitude sensitivities were 0.999, and bi-nasal sectors of ganglion cell complex thickness specificities were 0.999. This structural parameter had the highest diagnostic value (area under curve = 0.923). Significant associations were found between bi-nasal sectors with amplitude at 12′ (rho > 0.7, p < 0.01) and median deviation of the visual field (rho > 0.5, p < 0.01) at 3 months. Pre-surgical values of bi-nasal sectors and amplitude can predict post-surgically median deviation and amplitude (Oz, 12′) at 3 months with r2 > 0.5. Bi-nasal sectors of ganglion cell complex and visual evoked potentials P100 amplitude are efficient biomarkers of visual pathway damage for pituitary macroadenoma patients’ management. Pre-surgical values of the bi-nasal sector and visual evoked potentials’ amplitude could help to predict the restoration of parvocellular pathway traffic after decompression.

show abstract

Section: Discussionmentioning

confidence: 99%

Bi-nasal sectors of ganglion cells complex and visual evoked potential amplitudes as biomarkers in pituitary macroadenoma management

Hernández-Echevarría¹,

Cuétara-Lugo²,

Pérez-Benítez³

et al. 2022

Front. Integr. Neurosci.

View full text Add to dashboard Cite

show abstract

“…Contrast sensitivity can improve following pituitary adenoma resection, especially in patients with smaller contrast sensitivity deficits [30].…”

Section: Discussionmentioning

confidence: 99%

The efficacy of microperimetry and contrast sensitivity test in the diagnosis of optic chiasm compression due to pituitary adenomas

Sarnat-Kucharczyk

Kos–Kudła

Kajdaniuk

et al. 2019

Endokrynologia Polska

View full text Add to dashboard Cite

Introduction: The aim of the study was to determine which microperimetry and contrast sensitivity test parameters would prove the most valuable during diagnosing optic chiasm compression due to pituitary adenomas. Material and methods: A control group comprised healthy individuals (Group 1). Patients with pituitary macroadenoma were divided into two groups: Group 2-absent optic chiasm compression; and Group 3-present optic chiasm compression detected on contrastenhanced magnetic resonance imaging (MRI). Each group comprised 20 patients (40 eyes), i.e. a total of 60 patients (120 eyes) were examined. A complete ocular examination, intraocular pressure, microperimetry, contrast sensitivity test, kinetic Goldmann visual field, and static Octopus visual field test were performed. Results: Group 1 and 2 variables showed no statistically significant differences with respect to the mean sensitivity (MS) and mean defect (MD) in microperimetry. After dividing the microperimetry area into quadrants, a difference was shown in the mean sensitivity of the lower-nasal quadrant (MS LN) and mean defect of the lower-nasal quadrant (MD LN) between those groups. Receiver operating characteristic (ROC) curves analysis revealed that the microperimetry parameter-MS LN as well as row D and E contrast sensitivity test could be highly specific in the assessment of early damage of the optic nerve in patients suffering from pituitary adenoma. Conclusions: Microperimetry and contrast sensitivity test are non-invasive diagnostic investigations adjunctive to MRI, which facilitate detection of early chiasmal compression caused by pituitary adenomas.

show abstract

The Application of a New Maximum Color Contrast Sensitivity Test to the Early Prediction of Chiasma Damage in Cases of Pituitary Adenoma: The Pilot Study

Cited by 2 publications

References 16 publications

Bi-nasal sectors of ganglion cells complex and visual evoked potential amplitudes as biomarkers in pituitary macroadenoma management

Bi-nasal sectors of ganglion cells complex and visual evoked potential amplitudes as biomarkers in pituitary macroadenoma management

The efficacy of microperimetry and contrast sensitivity test in the diagnosis of optic chiasm compression due to pituitary adenomas

Contact Info

Product

Resources

About