Contrast lipocryolysis

Abstract

Alternative crystal structures are possible for all lipids and each different crystal structure is called a polymorphic form. Inter-conversion between polymorphisms would imply the possibility of leaning crystal formation toward the most effective polymorphism for adipocyte destruction. Food industry has been tempering lipids for decades. Tempering technology applied to lipocryolysis gave birth to “contrast lipocryolysis”, which involves pre- and post-lipocryolysis fat layer heating as part of a specific tempering protocol. In this study, we evaluated the skinfold thickness of 10 subjects after a single contrast lipocryolysis session and witnessed important and fast reductions.

Effectiveness and Safety of Contrast Cryolipolysis for Subcutaneous-Fat Reduction

“…A subsequent study [12] applied several temperature patterns (heating and cooling) in isolated rat adipocytes and observed an increase in the crystallization process when using contrast temperatures: heating-cooling-heating. Both processes, cooling and contrast temperatures, showed high potential to induce the cellular death of adipocytes through lipid crystallization [11, 33]. This research contributed to the development of the Lipocryo® technology (Clinipro, S.L.…”

“…One fact is clear: cold-induced lipid crystallization (crystal-structure formation) of the adipocytes occurs at temperatures around 8°C to 10°C, and it is a condition dependent on time and temperature; this seems to be the key to the results [11–13, 33, 35].…”

“…This method is based on the concept that lipid-rich tissues are more susceptible to injury through cold than the surrounding water-rich tissue is [10]. On the other hand, studies [11–13] have shown that, when alternating low temperatures and cycles of heating, the lipids in the adipocytes crystallize more easily, which is similar to what happens in the tempering process of the food industry, and this process may improve the clinical outcome of the treatment. This method is known as contrast lipocryolysis.…”

Heat Shock Lipolysis: Radiofrequency Combined with Cryolipolysis for the Reduction of Localized Subcutaneous Fat

“…e combination of pre-and postheating with cryolipolysis has already proven its effectiveness when compared with conventional lipolysis. Indeed, Pinto et al showed in their study a 42.45% improvement in fat reduction by using contrast lipolysis [8,10]. is phenomenon Dermatology Research and Practice 3 has also been observed by Pinto et al on in vitro adipocytes models.…”

“…Hence, pre-and postheating technology applied to lipocryolysis also called "contrast lipocryolysis," was evaluated in 10 subjects and showed significant fat reductions [10].…”