Effectiveness and Safety of Contrast Cryolipolysis for Subcutaneous-Fat Reduction

Abstract

Cryolipolysis is the noninvasive treatment of localized fat through cold-induced panniculitis. The purpose of the present study was to evaluate the safety and efficacy of contrast cryolipolysis for subcutaneous-fat reduction. Contrast cryolipolysis mixes the principles of conventional cryolipolysis and periods of heating in accordance with the contrast lipocryolysis process. Twenty-one subjects aged 34 ± 9 years were treated with contrast cryolipolysis in the regions of abdomen and flanks through the Polarys® device. Anthropometry, standardized photographs, measurements with a skinfold caliper, and diagnostic ultrasounds were performed at the baseline and during follow-ups at 30, 60, and 90 days after the treatment. The safety assessments included laboratory testing and monitoring of the adverse events. The level of significance for all tests was set at P < 0.05. No significant differences in weight and body mass index were found. The waist measurements at the baseline and 30-day follow-up had significant differences, as did the measurements at the 30-day and 60-day follow-ups. The skinfold and ultrasound measurements were significantly reduced in the treated areas in all the time points compared to the baseline. The laboratory results showed no significant changes from baseline. Temporary adverse effects were resolved spontaneously. This study confirmed that contrast cryolipolysis is safe and effective in reducing the fat layer and improving body contouring.

Systemic Effects of Cryolipolysis in Central Obese Women: A Randomized Controlled Trial

“…The current study results were in contrast with other studies, which concluded that Cryolipolysis is safe and effective in reducing the fat layer and improving body contouring but without any significant effect on lipid profile and liver enzymes [14,15,48]. However, the other studies' findings depended on either an application of one session of Cryolipolysis [15,48], or repeated applications [14] without any control of the diet, so the significant effect of Cryolipolysis group might also enhanced by the effect of low caloric diet. Also the current study was in contrast to another study, which approved that another reshaping modality increased the blood lipid level [49].…”

From Esthetic Medicine to Optimizing Reconstructive Outcome: A Feasibility Trial on Secondary Refinement of Fasciocutaneous Anterolateral Thigh Flaps with Cryolipolysis

“…23,24 The circumferences of the extremities were reduced significantly up to 2 cm, and the fat layer by almost one-third. Savacini et al observed similar results when cryolipolysis was used for esthetic flank contouring, 25 including a significant subcutaneous fat layer reduction, confirmed in further studies of the submental region (of 2.0 mm), the inner thighs (of 2.8 mm), the lateral thighs (of 2.6 mm), and the saddlebacks. 12,16,[25][26][27] Unfortunately, there is no comparative data available measuring the subcutaneous fat layer reduction after flap contouring by liposuction or partial excision.…”

Application of cryolipolysis in adipose tissue: A systematic review

“…On the contrary, studies concluded that cryolipolysis does not lead to significant changes in this outcome. However, these studies assessed the application of cryolipolysis alone, without any dietary control, which helps to reinforce results above 32–34 …”

“…However, these studies assessed the application of cryolipolysis alone, without any dietary control, which helps to reinforce results above. [32][33][34] Author, year…”