Contrast‐enhanced spectral mammography with a photon‐counting detector

Fredenberg, Erik; Hemmendorff, Magnus; Cederström, Björn; Åslund, Magnus; Danielsson, Mats

doi:10.1118/1.3371689

Cited by 91 publications

(146 citation statements)

References 40 publications

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“…PCD optimization was not complete, especially for selecting optimal energy threshold values. If optimal energy threshold values for PCD are set, it may produce better results [32]. It is our ongoing research to optimize PCD and to apply the proposed method to biological tissues.…”

Section: Discussionmentioning

confidence: 99%

A Quantification Method for Breast Tissue Thickness and Iodine Concentration Using Photon-Counting Detector

Han

2015

J Digit Imaging

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The purpose of contrast-enhanced digital mammography (CEDM) is to facilitate detection and characterization of the lesions in the breast using intravenous injection of an iodinated contrast agent. CEDM produces iodine images with gray levels proportional to iodine concentration at each pixel, which can be considered as quantification of iodine. While dual-energy CEDM requires an accurate knowledge of the thickness of compressed breast for the quantification, it is known that the accuracy of the built-in thickness measurement is not satisfactory. Triple-energy CEDM, which can provide a third image, can alleviate the limitation of dual-energy CEDM. If triple exposure technique is applied, it can lead to increased risk of motion artifact. An energy-resolving photoncounting detector (PCD) that can acquire multispectral X-ray images can reduce the risk of motion artifact. In this research, an easily implementable method for iodine quantification in breast imaging was suggested, and it was applied to the images of breast phantom with various iodine concentrations. The iodine concentrations in breast phantom simulate lesions filled with different iodine concentrations in the breast. The result shows that the proposed method can quantify the iodine concentrations in breast phantom accurately.

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Section: Discussionmentioning

confidence: 99%

A Quantification Method for Breast Tissue Thickness and Iodine Concentration Using Photon-Counting Detector

Han

2015

J Digit Imaging

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“…Manipulation of X-rays has enabled the production of specific incident energy spectrums (Spectral Shaping) and detection of photons in specific energy bands (Spectral Imaging) 77 .…”

Section: Spectralmentioning

confidence: 99%

Surfing the spectrum – what is on the horizon?

et al. 2013

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“…By implementing a second threshold, low-and high-energy photons can be distinguished from one another. This makes it possible to assign greater weight to the low-energy photons, which carry more contrast information [4]. On the contrary, energy integrating detectors will actually give the high-energy photons larger weight since the charge released by photons is proportional to its energy.…”

Section: Spectral Imagingmentioning

confidence: 99%

“…The former is expensive and often require injection of a contrast agent, and the latter is highly operator-dependent and time-consuming. Additionally, x-ray mammography provides images with high spatial resolution [4].…”

Section: Mammographymentioning

confidence: 99%

“…In a 2D mammogram for example, a tumor may be difficult to detect because normal tissue structures may obscure or hide it, and may also superimpose and appear as a pathology. Dual-energy substraction (DES) [8,9] is a method for reducing this anatomical background. In DES mammography, the anatomical background is suppressed by minimizing the contrast between adipose and glandular tissue.…”

Section: Spectral Imagingmentioning

confidence: 99%

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