Contrast-enhanced and unenhanced diffusion-weighted imaging of the breast at 3 T

Fanariotis, Michael; Tsougos, Ioannis; Vlychou, M.; Fezoulidis, Ioannis; Vassiou, Katherine

doi:10.1016/j.crad.2018.06.019

Cited by 8 publications

(7 citation statements)

References 27 publications

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“…Heacock et al 21 found that AP-MRI protocol may be more challenging to detect lesions presenting as NME. Second, in the past few years, there was no unified standard for slice thickness in DWI scanning; the slice thickness used in www.nature.com/scientificreports/ different studies was 3-5 mm 15,25,28,34,35 . Before 2019, the "European Society of Breast Radiology" established a minimum slice thickness of 4 mm 36 .…”

Section: Discussionmentioning

confidence: 99%

Performance of abbreviated protocols versus unenhanced MRI in detecting occult breast lesions of mammography in patients with dense breasts

Chen

Shao

et al. 2022

Sci Rep

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To assess the diagnostic ability of abbreviated protocols of MRI (AP-MRI) compared with unenhanced MRI (UE-MRI) in mammographically occult cancers in patients with dense breast tissue. The retrospective analysis consisted of 102 patients without positive findings on mammography who received preoperative MRI full diagnostic protocols (FDP) between January 2015 and December 2018. Two breast radiologists read the UE, AP, and FDP. The interpretation times were recorded. The comparisons of the sensitivity, specificity and area under the curve of each MRI protocol, and the sensitivity of these protocols in each subgroup of different size tumors used the Chi-square test. The paired sample t-test was used for evaluating the difference of reading time of the three protocols. Among 102 women, there were 68 cancers and two benign lesions in 64 patients and 38 patients had benign or negative findings. Both readers found the sensitivity and specificity of AP and UE-MRI were similar (p > 0.05), whereas compared with FDP, UE had lower sensitivity (Reader 1/Reader 2: p = 0.023, 0.004). For different lesion size groups, one of the readers found that AP and FDP had higher sensitivities than UE-MRI for detecting the lesions ≤ 10 mm in diameter (p = 0.041, p = 0.023). Compared with FDP, the average reading time of UE-MRI and AP was remarkably reduced (p < 0.001). AP-MRI had more advantages than UE-MRI to detect mammographically occult cancers, especially for breast tumors ≤ 10 mm in diameter.

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Section: Discussionmentioning

confidence: 99%

Performance of abbreviated protocols versus unenhanced MRI in detecting occult breast lesions of mammography in patients with dense breasts

Chen

Shao

et al. 2022

Sci Rep

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“…So far, we have not found the study of AP on non-mass lesions. Second, in the past few years, there was no uni ed standard for slice thickness in DWI scanning; the slice thickness used in different studies was 3-5 mm 15,25,28,33,34 . Before 2019, the "European Society of Breast Radiology" established a minimum slice thickness of 4 mm 35 .…”

Section: Discussionmentioning

confidence: 99%

Performance of Abbreviated Protocols Versus Unenhanced MRI in Detecting Occult Breast Lesions of Mammography in Patients with Dense Breasts

Zhao

Chen

Shao

et al. 2021

Preprint

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Objective: To assess the diagnostic ability of abbreviated protocols of MRI (AP-MRI) compared with unenhanced MRI (UE-MRI) in mammographically occult cancers in patients with dense breast tissue.Materials and Methods: The retrospective analysis consisted of 102 patients without positive findings on mammography who received preoperative MRI full diagnostic protocols (FDP) between January 2015 and December 2018. Two breast radiologists read the UE, AP, and FDP. The interpretation times were recorded. The comparisons of the sensitivity, specificity and area under the curve of each MRI protocol, and the sensitivity of these protocols in each subgroup of different size tumors used the Chi-square test. The paired sample t-test was used for evaluating the difference of reading time of the three protocols.Results: Among 102 women, there were 68 cancers and two benign lesions in 64 patients and 38 patients had benign or negative findings. Both readers found the sensitivity and specificity of AP and UE-MRI were similar (p>0.05), whereas compared with FDP, UE had lower sensitivity (Reader 1/Reader 2: p=0.023, 0.004). For different lesion size groups, one of the readers found that AP and FDP had higher sensitivities than UE-MRI for detecting the lesions ≤10 mm in diameter (p=0.041, p=0.023). Compared with FDP, the average reading time of UE-MRI and AP was remarkably reduced (p < 0.001).Conclusion: AP-MRI had more advantages than UE-MRI to detect mammographically occult cancers, especially for breast tumors ≤10 mm in diameter.

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“…For data of two readers presented in a paper, mean values of both readers were included [15][16][17][18]. From multiple b-value combinations [19][20][21][22][23] or multiple cut-off values [3,24,25] presented, the outcome showing highest combination of sensitivity and specificity was included. When both mass and nonmass lesions were analyzed separately, only mass lesions were included [3,16,26,27].…”

Section: Data Collectionmentioning

confidence: 99%

“…The number of malignant and benign lesions ranged from 14-259 and 8-161, respectively, with a mean of 61 malignant and 36 benign lesions per study subset. Seven study subsets were categorized as BTTS1: whole breast tumor tissue selection [35,[38][39][40][41][42][43], 22 as BTTS2: subtracted whole breast tumor tissue selection [15][16][17]20,23,36,37,[44][45][46][47][48][49][50][51][52][53][54][55][56][57][58], 19 as BTTS3: circular breast tumor tissue selection [18,19,21,24,25,36,[59][60][61][62][63][64][65][66][67][68][69][70][71] and 17 as BTTS4: lowest diffusion breast tumor tissue selection…”

Section: Characteristics Of the Studies Includedmentioning

confidence: 99%

Diagnostic performance of breast tumor tissue selection in diffusion weighted imaging: A systematic review and meta-analysis

et al. 2020

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Background Several methods for tumor delineation are used in literature on breast diffusion weighted imaging (DWI) to measure the apparent diffusion coefficient (ADC). However, in the process of reaching consensus on breast DWI scanning protocol, image analysis and interpretation, still no standardized optimal breast tumor tissue selection (BTTS) method exists. Therefore, the purpose of this study is to assess the impact of BTTS methods on ADC in the discrimination of benign from malignant breast lesions in DWI in terms of sensitivity, specificity and area under the curve (AUC). Methods and findings In this systematic review and meta-analysis, adhering to the PRISMA statement, 61 studies, with 65 study subsets, in females with benign or malignant primary breast lesions (6291 lesions) were assessed. Studies on DWI, quantified by ADC, scanned on 1.5 and 3.0 Tesla and using b-values 0/50 and � 800 s/mm 2 were included. PubMed and EMBASE were searched for studies up to 23-10-2019 (n = 2897). Data were pooled based on four BTTS methods (by definition of measured region of interest, ROI): BTTS1: whole breast tumor tissue selection, BTTS2: subtracted whole breast tumor tissue selection, BTTS3: circular breast tumor tissue selection and BTTS4: lowest diffusion breast tumor tissue selection. BTTS methods 2 and 3 excluded necrotic, cystic and hemorrhagic areas. Pooled sensitivity, specificity and AUC of the BTTS methods were calculated. Heterogeneity was explored using the inconsistency index (I 2) and considering covariables: field strength, lowest bvalue, image of BTTS selection, pre-or post-contrast DWI, slice thickness and ADC threshold. Pooled sensitivity, specificity and AUC were

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Contrast-enhanced and unenhanced diffusion-weighted imaging of the breast at 3 T

Cited by 8 publications

References 27 publications

Performance of abbreviated protocols versus unenhanced MRI in detecting occult breast lesions of mammography in patients with dense breasts

Performance of abbreviated protocols versus unenhanced MRI in detecting occult breast lesions of mammography in patients with dense breasts

Performance of Abbreviated Protocols Versus Unenhanced MRI in Detecting Occult Breast Lesions of Mammography in Patients with Dense Breasts

Diagnostic performance of breast tumor tissue selection in diffusion weighted imaging: A systematic review and meta-analysis

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