Continuous measurement of blood gases using a combined electrochemical and spectrophotometric sensor

Abstract

The use of a combined electrochemical and fibreoptic continuous intra-arterial blood gas sensor is described. The purpose of the study was to evaluate the performance of the sensor in 10 patients in the intensive therapy unit following insertion through a femoral arterial cannula. To our knowledge this is the first published study on the valuation of an intravascular blood gas sensor through a femoral arterial cannula. A total of 71 sets of data comparing the sensor with the blood gas analyser were obtained. The bias and precision for pH, PCO2 and PO2 were 0.006 and 0.07 pH units, 0.2 and 1.65 kPa (4.6% and 29%) and 0.8 and 2.7 kPa (5.1% and 14.3%) respectively. There was a degree of imprecision of the PCO2 sensor, the reasons for which are discussed. In summary, the intra-arterial sensor functioned well when inserted into the femoral artery in post-cardiopulmonary bypass patients. There were no complications attributable to sensor placement.

Monitoring Tissue Oxygenation during Resuscitation of Major Burns

“…The device, originally designed for continuous intra-arterial blood gas and pH measurement, 27,46 has since been validated and widely used experimentally for the measurement of tissue O 2 and CO 2 tensions. [47][48][49][50] Silastic tubing was used on the basis of the methodology of Ninikoski et al 51 and Ninikoski and Hunt.…”

Accuracy and clinical performance of a continuous intra-arterial blood-gas monitoring system during thoracoscopic surgery

“…Unfortunately, the PT7 system has been validated clinically by only one team of investigators in collaboration with the manufacturer. [3][4][5] Assessing accuracy and clinical performance of the PT7 system independently is therefore important. In thoracoscopy, using OLV, we had the opportunity to assess the accuracy of the PT7 system over a wide range of arterial PO 2 (6.1-61.1 kPa), PCO 2 (4.1-9.5 kPa) and pH (7.19-7.50) values.…”

“…The Paratrend 7 system (PT7), however, has been validated by only one group of authors in an experimental animal study 2 and, for limited PO 2 , PCO 2 and pH ranges, in the intensive care unit and during cardiac surgery. [3][4][5] This study was performed to evaluate prospectively the clinical accuracy and performance of the Paratrend 7 intra-arterial blood-gas monitoring system during thoracoscopy over a wide range of PO 2, PCO 2 and pH values.…”

Continuous Monitoring of Fetal pH, pO₂ and pCO₂ Using a Fiberoptic Multiparameter Sensor in Animal Models Reproducing in utero Conditions

“…It provides continuous measurements of pO 2 , pCO 2 , pH, and temperature and has been successfully used in both adult and neonatal intensive care situations [7,8]. Validation of the accuracy of this sensor has been demonstrated in vivo in the physiologic range for postnatal values [5,[9][10][11] but never focussed on the low range of pO 2 present in fetal life. Additionally, the efficacy of this system has never been tested in utero.…”