Continuous infusion of propofol in calves: bispectral index and hemodynamic effects

Deschk, Maurício; Wagatsuma, Juliana Tessália; Araújo, Maria Amélia Máximo de; Santos, Guilherme Gonçalves Fabretti; Sergio, S. R.; Abimussi, Caio José Xavier; Siqueira, Carlos Eduardo de; Motta, J. C. Lemos; Perri, S. H. V.; Santos, Paulo Sérgio Patto dos

doi:10.1111/vaa.12302

Cited by 10 publications

(5 citation statements)

References 24 publications

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“…This demonstrated that the results from the BIS assessment was directly dependent upon the anesthetic protocol which was used for cattle. Conversely, the study by DESCHK et al (2015), who also used the same protocol and assessed values that were very similar to those of the present study, suggested that the low infusion rate of fentanyl was insufficient to further depress the CNS of the animals. This resulted in a decrease in the BIS values, and/or a BIS value of approximately 50 in calves anesthetized with CI of propofol.…”

Section: Discussionsupporting

confidence: 76%

“…To our knowledge, this is the first report of the administration of a CRI of propofol combined with fentanyl in calves, based on the literature review performed. The propofol dose which was used was retrieved from DESCHK et al (2015), who assessed two different propofol infusion rates in calves (0.6mg kg -1 min -1 and 0.8mg kg -1 min -1 ), whereby the best results were assessed using the 0.6mg kg -1 min -1 infusion rate in this study. The necessity of adding an analgesic to this protocol as an adjunct method for TIVA was identified in the present study.…”

Section: Discussionmentioning

confidence: 99%

“…0.001mg kg -1 hour -1 infusion rate, for 60 minutes. The use of these infusion rates was described by DESCHK et al (2015), TRANQUILLI et al (2007) and pilot studies performed at our institution.…”

Section: Methodsmentioning

confidence: 99%

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Bispectral index assessment in calves subjected to the continuous infusion of propofol combined with fentanyl administration

et al. 2017

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The aim of this study was to evaluate the bispectral index (BIS) effects in calves through continuous infusion of propofol with or without fentanyl. Eight Holstein male calves (ages from six to twelve months old) with an average weight of 123±18kg were used. All animals participated in both groups, always keeping a minimum interval of one week between the anesthetic procedures; the calves were randomly distributed between groups. Anesthesia was induced with an intravenous (IV) dose of propofol of 5mg kg-1 in control group (GP) or with propofol (4mg kg-1) associated with IV fentanyl 0.001mg kg-1(GF). All the calves were positioned in right lateral recumbency and were allowed to spontaneously breathe room air. Subsequently, the anesthesia was maintained by continuous infusion of propofol at the rate of 0.6mg kg-1 min-1 IV in GP, and associated with the infusion of fentanyl 0.001mg kg-1 hour-1 in GF. Measurements of BIS, signal quality index (SQI) and electromyography (EMG) were evaluated before anesthesia induction (TB), and at 15, 30, 45 and 60 minutes after the beginning of continuous drugs infusion (T15, T30, T45 and T60, respectively). The heart rate (HR), respiratory rate (f), end-tidal carbon dioxide tension (ETCO2) and recovery times were evaluated as well. No significant differences were observed between the groups in the BIS variables and the recovery time was longer in GF. Co-administration of propofol and fentanyl infusions, at the doses reported here, did not change the values of BIS in cattle, but delayed the recovery time.

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Section: Discussionsupporting

confidence: 76%

Section: Discussionmentioning

confidence: 99%

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Bispectral index assessment in calves subjected to the continuous infusion of propofol combined with fentanyl administration

et al. 2017

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“…Internal fixation techniques using plates and intramedullary pins have been used successfully for the repair of humeral fractures in cattle [3, 12]. However, plate fixation is rarely done in cattle, because it requires expensive implants and equipment, specialized surgical facilities, and anesthetic support for orthopedic surgery [9].…”

mentioning

confidence: 99%

“…In the previous reports [18] and the present case, additional intramuscular administration of xylazine was necessary to maintain sedation during the surgery. Continuous infusion of propofol may be useful for maintenance anesthesia in calves [3]; however, it is necessary to include analgesia for invasive surgical procedures. Further studies are needed to establish a protocol for continuous infusion of propofol for ESF or TPC surgery in calves.…”

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confidence: 99%

Humeral fracture in a Japanese Black calf repaired by closed approach and two methods of external skeletal fixation

Yamagishi

Kajiwara²,

Shibano

et al. 2017

The Journal of Veterinary Medical Science

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A healthy 71-day-old female Japanese Black calf was evaluated for fracture of the left humerus. The left humeral fracture was treated by closed repair and unilateral external skeletal fixation (ESF) with an epoxy putty fixator. The calf was active, and eight days after surgery slipped and fell, resulting in breakage of the ESF. The calf underwent repair by transfixation pinning and casting (TPC), which is an alternative to the ESF method. The TPC was removed 37 days after the first surgery, and the calf could bear weight on the left forelimb while walking. This case suggests that recovery after closed repair with TPC for a humeral fracture in an active calf can be successfully managed on the farm.

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Anesthetic Depth Monitoring and Electroencephalography

Norkus

2024

Veterinary Anesthesia and Analgesia

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Continuous infusion of propofol in calves: bispectral index and hemodynamic effects

Cited by 10 publications

References 24 publications

Bispectral index assessment in calves subjected to the continuous infusion of propofol combined with fentanyl administration

Bispectral index assessment in calves subjected to the continuous infusion of propofol combined with fentanyl administration

Humeral fracture in a Japanese Black calf repaired by closed approach and two methods of external skeletal fixation

Anesthetic Depth Monitoring and Electroencephalography

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