Continuous Critical Care and Long-Term Noninvasive Ventilatory Support for Patients With Neuromuscular Disease

Cheng, Glen; Bach, John R.

doi:10.1378/chest.08-1895

Cited by 3 publications

(1 citation statement)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The excluded publications comprised 2 non-randmomised studies, 20 21 6 observational studies, [22][23][24][25][26][27] 11 retrospective studies, 4 12 16 28-35 2 narrative reviews 36 37 and 3 letters to the editor. [38][39][40] The non-randomised studies were not included as eligible despite having a control group, because they did not compare different weaning protocols. In both cases, patients with NMD were submitted to pressure support weaning protocol and the outcomes measured were different from those included in the methods.…”

Section: Resultsmentioning

confidence: 99%

Weaning from mechanical ventilation in people with neuromuscular disease: a systematic review

et al. 2021

View full text Add to dashboard Cite

ObjectiveThis systematic review aimed in assessing the effects of different weaning protocols in people with neuromuscular disease (NMD) receiving invasive mechanical ventilation, identifying which protocol is the best and how different protocols can affect weaning outcome success, duration of weaning, intensive care unit (ICU) and hospital stay and mortality.DesignSystematic review.Data sourcesElectronic databases (MEDLINE, EMBASE, Web of Science and Scopus) were searched from January 2009 to August 2020.Eligibility criteria for selecting studiesRandomised controlled trials (RCTs) and non-RCT that evaluated patients with NMD (adults and children from 5 years old) in the weaning process managed with a protocol (pressure support ventilation; synchronised intermittent mandatory ventilation; continuous positive airway pressure; ‘T’ piece).Primary outcomeWeaning success.Secondary outcomesWeaning duration, ICU stay, hospital stay, ICU mortality, complications (pneumothorax, ventilation-associated pneumonia).Data extraction and synthesisTwo review authors assessed the titles and the abstracts for inclusion and reviewed the full texts independently.ResultsWe found no studies that fulfilled the inclusion criteria.ConclusionsThe absence of studies about different weaning protocols for patients with NMD does not allow concluding the superiority of any specific weaning protocol for patients with NMD or determining the impact of different types of protocols on other outcomes. The result of this review encourages further studies.PROSPERO registration numberCRD42019117393.

show abstract