Continuing surgical care in cancer patients during the nationwide lockdown in the COVID‐19 pandemic—Perioperative outcomes from a tertiary care cancer center in India

Pai, Esha; Chopra, S.; Mandloi, Deepak; Upadhyay, Arvind Kumar; Prem, Amar; Pandey, Durgatosh

doi:10.1002/jso.26134

Cited by 16 publications

(20 citation statements)

References 13 publications

(12 reference statements)

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“…The subgroup analysis showed that dementia was the most prevalent comorbidity followed by hypertension and Diabetes Mellitus. However, the nding of this study was contrary to other studies conducted on the prevalence of comorbidities among patients with COVID-19 where hypertension was the most prevalent comorbidity among patients with COVID-19 (21,25,45,91). This discrepancy might be explained by the inclusion of only one study in this Meta-Analysis that reported a high prevalence of dementia compared to other comorbidities.…”

Section: Discussioncontrasting

confidence: 87%

“…Body of evidence showed that patients visiting the health institution during the COVID-19 pandemic decrease signi cantly despite requiring medical care which affects signi cantly the non-COVID-19 patients' hospital admission (22)(23)(24)(25)(26).…”

Section: Introductionmentioning

confidence: 99%

“…Some studies showed that perioperative mortality of patients with COVID-19 was very high (23,25,39,(48)(49)(50) while some studies failed to identify signi cant mortality among patients with COVID-19 undergoing surgical procedures (21,47,51,52).…”

Section: Introductionmentioning

confidence: 99%

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Global Prevalence of Perioperative Outcomes of Surgical Patients with COVID-19: A Systematic Review and Meta-Analysis

Abate¹,

Mantefardo²,

Basu³

2020

Preprint

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Background: Surgery during the COVID-19 pandemic is too challenging globally especially for low and middle-income countries in which the limping health care system is broken with low testing capacity, sub-optimal postoperative care, lack of anesthesia machine filters, and limited personal protective equipment. Body of evidence is lacking on the prevalence of perioperative outcomes of patients with COVID-19. Therefore, this study is aimed to provide the global prevalence of perioperative outcomes of patients with COVID-19.Methods: A comprehensive search was conducted in PubMed/Medline; Science direct and LILACS from December 2019 to August 2020 without language restriction. The Heterogeneity among the included studies was checked with forest plot, χ2 test, I2 test, and the p-values. All observational studies reporting the prevalence of mortality were included.Results: A total of 515 articles were identified from different databases and 50 articles were selected for evaluation after the successive screening. Twenty-three articles with 2947 participants were included. The Meta-Analysis revealed that the global prevalence of perioperative mortality among COVID-19 patients was 20% (95% CI: 15 to 26). The Meta-Analysis also revealed that the rate of postoperative ICU admission was 15% (95% confidence interval (CI):10 to 21).Conclusion: There is one death for every five COVID-19 patients undergoing surgical procedures which entails mitigating strategies to decrease perioperative mortality, provide less risky anesthetic techniques, and alternative management other than surgical procedures.Registration: This systematic review and meta-analysis was registered in Prospero's international prospective register of systematic reviews (CRD42020203362) on August 10, 2020.

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Section: Discussioncontrasting

confidence: 87%

Section: Introductionmentioning

confidence: 99%

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Global Prevalence of Perioperative Outcomes of Surgical Patients with COVID-19: A Systematic Review and Meta-Analysis

Abate¹,

Mantefardo²,

Basu³

2020

Preprint

View full text Add to dashboard Cite

show abstract

mentioning

confidence: 99%

“…Some studies showed that perioperative mortality of patients with COVID-19 was very high [30,32,46,[55][56][57] while some studies failed to identify signi cant mortality among patients with COVID-19 undergoing surgical procedures [28,54,58,59].…”

mentioning

confidence: 99%

Postoperative mortality among surgical patients with COVID-19: A systematic review and meta-analysis

Abate

Mantefardo

Basu

2020

Preprint

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Background: The coronavirus disease 2019 (COVID-19) pandemic puts perioperative providers and staff at risk of viral exposure to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) during aerosol-generating procedures, particularly in asymptomatic carriers. However, the perioperative risk for adverse outcomes in SARS-CoV-2 infected patients remain uncertain and the topic of debate. The current study was designed to determine the postoperative mortality in COVID-19 patients based on a systematic review and meta-analysis of the global published peer-reviewed literature.Methods: A comprehensive search was conducted in PubMed/Medline; Science direct and LILACS from December 29, 2019, to August15, 2020, without language restriction. All observational studies reporting the prevalence of mortality were included while case reports and reviews were excluded. The data from each study were extracted with two independent authors with a customized format excel sheet and the disagreements were resolved by the third author. The methodological quality of included studies was evaluated using a standardized critical appraisal Tool adapted from the Joanna Briggs Institute.Results: A total of 715 articles were identified from different databases and 45 articles were selected for evaluation after the successive screening. Twenty-three articles with 2947 participants were included. The meta-analysis revealed a very high global rate of postoperative mortality among COVID-19 patients of 20% (95% CI: 15 to 26) and a postoperative ICU admission rate of 15% (95% confidence interval (CI):10 to 21). Conclusion: The unexpected high postoperative mortality rate in SARS-CoV-2 infected patients of 20% in the global literature mandates further scrutiny in assuring appropriate surgical indications and perioperative surgical safety measures in this vulnerable cohort of patientsRegistration: This systematic review and meta-analysis was registered in Prospero's international prospective register of systematic reviews (CRD42020203362) on August 10, 2020.

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