Contiguous lesions in lentigo maligna

Dalton, Scott R.; Gardner, Timothy L.; Libow, Lester F.; Elston, Dirk M.

doi:10.1016/j.jaad.2004.11.063

Cited by 48 publications

(33 citation statements)

References 18 publications

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“…따라서 외부의 자극을 줄이거나 그 신호의 전달을 차 단하는 방법을 통해 멜라닌의 생성을 줄일 수 있다. 또한 멜라닌 생성효소인 타이로시네이즈의 합성을 억 제하거나 그 활성을 저해하여 멜라닌의 생성을 감소 시킬 수 있다 [1][2][3]. 많은 미백연구에서 시험관 내 실험 에서 좋은 결과를 보이는 화합물들이 임상적으로 충 분한 효과를 내기 위해서는 화합물의 안정성이나 피 부적용시의 문제점 등을 고려한 연구가 필요하다 [4].…”

Section: )unclassified

Whitening Effects of Adamantyl Benzamide Derivatives

백흥수¹,

안수미²,

우병영³

et al. 2013

Journal of the Society of Cosmetic Scientists of Korea

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The structure activity relationship of polyhydroxylated benzamide derivatives for whitening effects was examined. The adamantyl benzamide derivatives with catechol (3,4-dihydroxyphenyl) of B-ring part showed good anti-melanogenesis activity, but the inhibitory activity of mono-hydroxyphenyl (3-OH or 4-OH) or 3,4-dimethoxyphenyl substituted derivatives was decreased or lost. Therefore the catechol unit was appeared to be the crucial factor for the inhibition of melanogenesis. And the existence of 2-OH of A-ring part had minor influence on the activity, the length of carbon chain between A-ring and B-ring was also not the major factor for the anti-melanogenesis activity.

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Section: )unclassified

Whitening Effects of Adamantyl Benzamide Derivatives

백흥수¹,

안수미²,

우병영³

et al. 2013

Journal of the Society of Cosmetic Scientists of Korea

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“…[65][66][67][68] Collision with nonmelanocytic pigmented lesions such as benign lentigines and pigmented actinic keratosis occurs in almost half of lesions of lentigo maligna, and represents another important pitfall. 69 Although benign junctional nevi are not uncommon in patients older than 60 years, they rarely occur on the face and broad junctional lesions on older patients should always be viewed with suspicion. 70,71 It is important to communicate the breadth of the lesion to the pathologist.…”

Section: Lentigo Malignamentioning

confidence: 99%

Practical advice regarding problematic pigmented lesions

Elston

2012

Journal of the American Academy of Dermatology

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“…These processes are involved in local hyperpigmentation such as melasma 2 and lentigo. 3 Therefore, the inhibition of tyrosinase to treat the pigmentation disorders has been a recent subject of many studies. Kojic acid 4 (1) is well known as one of the most popular tyrosinase inhibitors and it has been widely used as a skin-whitening agent.…”

Section: Tyrosinasementioning

confidence: 99%