Contemporary survival trends and aetiological characterization in non‐ischaemic dilated cardiomyopathy

Abstract

Contemporary survival trends in dilated cardiomyopathy (DCM) are largely unknown. The aim of this study is to investigate clinical descriptors, survival trends and the prognostic impact of aetiological characterization in DCM patients.

February 2021 at a glance: focus on amyloidosis, myocarditis and cardiomyopathy

“…Over the last years, improvement in survival was observed in patients with dilated cardiomyopathy, with many patients with new-onset cardiomyopathy who may show reverse remodelling. 13,14 In TRED-HF, withdrawal of pharmacological treatment for HF in patients with recovered dilated cardiomyopathy was associated with relapses in 44% of patients. 15 In a further analysis by cardiac magnetic resonance, treatment withdrawal resulted in early ventricular remodelling with an increase in myocardial mass and a reduction in global longitudinal strain.…”

July 2020 at a glance: focus on imaging and cardiomyopathies

“…Data on epidemiology of cardiomyopathies are limited 1–3 . Merlo et al 4 . showed a reduction in mortality, heart transplantation, left ventricular (LV) assist device implantation and sudden cardiac death in the last decade, compared with the previous ones, in patients with non‐ischaemic dilated cardiomyopathy (DCM).…”

Dilated Cardiomyopathy: A Paradigm of Revolution in Medicine

“…DCM currently carries a relatively benign outcome, significantly improved with respect to the past decades. Contemporary analysis shows the survival/free from heart transplant rate beyond 85% at 10-year follow-up [ 2 ]. Nevertheless, the knowledge regarding pathophysiology, aetiology, diagnostic workup and prognostic stratification of DCM is rapidly and progressively evolving, reflecting the clinical management of the disease that remains extremely challenging in daily practice [ 3 ].…”

“…Indeed, DCM patients are often relatively young at the time of diagnosis (between their 30s and 50s) with a low-co-morbidity profile, and their current diagnostic workup and risk stratification is characterized by several pitfalls (particularly regarding the arrhythmic risk). Consequently, a not-negligible proportion of DCM patients still experience an unfavourable prognosis, particularly in the short-term [ 2 ].…”