Contemporary epidemiology of gout and hyperuricemia in community elderly in Beijing

Abstract

Our study showed that the prevalence of both gout and hyperuricemia in Beijing remains substantial. The prevalence in the Hui population was higher than other ethnic groups. The traditional risk factors were strong risk factors for gout and hyperuricemia in China.

Gender differences in the association between hyperuricemia and diabetic kidney disease in community elderly patients

“…The overall rate of hyperuricemia was 20.5% (males: 17.2%, females: 23.0%) in this study based on EHR, which was higher than other reports of the general Chinese elderly population in Beijing (18.1% overall; males: 16.0%, females: 19.4%) -with the same diagnostic criteria (Lu et al, 2014). However the rate of hyperuricemia was close to that of another study in Songjiang District of Shanghai in general diabetic patients of 21.88%, especially female patients of 22.7%.…”

“…The rate of hyperuricemia increased and the mean eGFR decreased with increased age in both men and women, especially in older women. These gender difference was observed in other studies as well and was suggested to relate to natural aging, the decline in female hormone levels in older women and the reduced excretion of uric acid from the kidney (Chang et al, 2010;Krishnan, Bennett, & Chen, 2014;Liu et al, 2014;Lu et al, 2014;Yoshitomi et al, 2014).…”

Prevalence and Incidence of Frailty in Community‐Dwelling Older People: Beijing Longitudinal Study of Aging II

“…Three urban districts and one rural county were randomly selected from 18 administrative districts or counties in Beijing. Residents aged 55 and older who had lived in the selected communities for longer than 1 year were invited to participate . Informed consent was obtained from participants, and the research ethics committee of Xuanwu Hospital of Capital Medical University provided ethics approval before study initiation.…”

Results of an Observational Cohort Study of Hyperuricemia as a Predictor of Poor Physical Performance in the Elderly

“…Although different thresholds can be used, the upper limit of the reference range for men is usually set at 7 mg/dl and for women 6 mg/dl . The tendency to develop hyperuricemia increases with age, particularly due to a decrease in the excretion of uric acid, predisposing older adults as more likely to have hyperuricemia . Hyperuricemia could depend on several factors, including age, sex, obesity, metabolic and cardiovascular diseases (CVDs), dietary habits (particularly heavy alcohol drinking), and cancer .…”