Contaminated Breast Milk: A Source of Klebsiella Bacteremia in a Newborn Intensive Care Unit

Donowitz, Leigh G.; Marsik, Frederic J.; Fisher, Karen A.; Wenzel, Richard P.

doi:10.1093/clinids/3.4.716

Cited by 80 publications

(32 citation statements)

References 19 publications

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“…Studies have reported K. pneumoniae outbreaks with a wide variety of objects such as ultrasonography gel, intravenous solutions containing dextrose, contaminated breast milk, and bath soap. [23242526] Since some of these factors can be relevant in our ICU, their identification and prevention can be useful to reduce the K. pneumoniae infections in our patients. Our study also showed a high incidence of Klebsiella in the UTIs and the same has also been described in studies reported from other parts of the world.…”

Section: Discussionmentioning

confidence: 99%

Epidemiology and characteristics of nosocomial infections in critically ill patients in a tertiary care intensive care unit of Northern India

2017

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Background and Aims:The prevalence of nosocomial infection is higher in the Intensive Care Unit (ICU) than other areas of the hospital. The present observational study was undertaken to describe the epidemiology and characteristics of nosocomial infections acquired in a tertiary care ICU and the impact of the various risk factors in their causation.Materials and Methods:A retrospective study was conducted on the prospectively collected data of 153 consecutive patients admitted in a tertiary care ICU between July 2014 and December 2015. The primary objective was to assess the epidemiology of ICU-acquired bacterial infections in terms of the incidence of new infections, causative organism, and site. The secondary end point was to assess the risk factors for developing ICU-acquired infections.Results:Out of the 153 patients enrolled in the study, 87 had an ICU-acquired nosocomial infection (58.86%). The most common organism responsible for infection was Klebsiella pneumoniae (37%), and the most common infection was pneumonia (33%). The duration of mechanical ventilation and length of ICU stay were significantly prolonged in patients developing nosocomial infections. There was no difference in mortality between the groups. The multivariate analyses identified intubation longer than 7 days, urinary catheterization >7 days, duration of mechanical ventilation more than 7 days, and ICU length of stay longer than 7 days as independent risk factors for nosocomial infections.Conclusion:The study demonstrated a high incidence of nosocomial infection in the ICU and identified the risk factors for acquisition of nosocomial infections in the ICU.

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Section: Discussionmentioning

confidence: 99%

Epidemiology and characteristics of nosocomial infections in critically ill patients in a tertiary care intensive care unit of Northern India

2017

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“…Between 60 and 80 % of samples of expressed human milk are contaminated with high amounts of skin contaminants, including coagulase-negative staphylococci (CoNS), alphahaemolytic streptococci and diphteroids [23,28], or pathogens such as cytomegalovirus or Escherichia coli [36], Serratia marcescens [13], Pseudomonas aeruginosa [14] or Klebsiella species [10].…”

Section: Introductionmentioning

confidence: 99%

Impact of pasteurization on the antibacterial properties of human milk

Gysel¹,

Cossey

Fieuws³

et al. 2012

Eur J Pediatr

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“…Other isolates of KLE from a previous multicenter study within the Polish Neonatal Network [7] were added to the genetic typing as strains that are material for comparison. It was shown that three of them [3][4][5] have different, unique restriction…”

Section: The Microbiological Analysismentioning

confidence: 99%

“…Breast milk transmission of such bacteria like Staphylococcus aureus [1], Streptococcus group B [2], Listeria sp. [3], E.coli [4], KLP [5] has been documented. Breast milk can be considered as a potential source of infection in newborns with recurrent infections or in the case of infection occurring simultaneously in siblings [6].…”

Section: Introductionmentioning

confidence: 99%

Klebsiella pneumoniae in Breast Milk-A Cause of Sepsis in Neonate

Pawlik¹,

Chmielarczyk²,

Lorenc³

et al. 2017

Arch Med

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Objective: The aim of the analysis was to present two cases of a late onset sepsis (LOS) caused by Klebsiella pneumoniae (KLE) recognized in prematurely delivered siblings, born within the interval of one year. Study Design and Result:It was a retrospective study. The first child was born after 32 weeks of pregnancy and the gestational age of the second infant was 29 weeks of pregnancy and died in the course of sepsis without positive blood culture examination. In the second child, sepsis with the same clinical signs was diagnosed, the strains of KLE were isolated from the blood and from the mother's breast milk: the strains were identical, confirmed with PFGE. Conclusion:Presented results suggest that the source of infections in both siblings was contaminated breast milk. The targeted therapy used in the mother allowed breastfeeding the child.

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Contaminated Breast Milk: A Source of Klebsiella Bacteremia in a Newborn Intensive Care Unit

Cited by 80 publications

References 19 publications

Epidemiology and characteristics of nosocomial infections in critically ill patients in a tertiary care intensive care unit of Northern India

Epidemiology and characteristics of nosocomial infections in critically ill patients in a tertiary care intensive care unit of Northern India

Impact of pasteurization on the antibacterial properties of human milk

Klebsiella pneumoniae in Breast Milk-A Cause of Sepsis in Neonate

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