Contact Dermatitis From Opium Derivatives

Jordon, James W.; Osborne, Earl D.

doi:10.1001/jama.1939.02800470031007

Cited by 8 publications

(3 citation statements)

References 6 publications

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“… e Some examples of literature given; data not specified because of difficulties in assessing very early literature. In this literature, (occupational) contact dermatitis and (in some cases) systemic allergic dermatitis to opium alkaloids, including codeine, morphine, apomorphine, and ethylmorphine have been described (eg, refer 131‐136 ; reviews in refs 131,133 131 …”

Section: Systemic Allergic Dermatitis From Systemic Drugsmentioning

confidence: 99%

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Systemic allergic dermatitis (systemic contact dermatitis) from pharmaceutical drugs: A review

Groot¹

2021

Contact Dermatitis

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The literature on systemic allergic dermatitis (SAD; also known as systemic contact dermatitis) is reviewed. Both topical drugs (from absorption through mucosae or skin) and systemic drugs (oral, parenteral, rectal) may be responsible for the disorder. The topical route appears to be rare with 41 culprit topical drugs found to cause SAD in 95 patients. Most reactions are caused by budesonide (especially from inhalation), bufexamac, and dibucaine. SAD from systemic drugs is infrequent with 95 culprit drugs found to cause SAD in 240 patients. The drugs most frequently implicated are mitomycin C, methylprednisolone (salt, ester), and hydrocortisone (salt). The largest group of culprit drugs consisted of corticosteroids (19%), being responsible for >30% of the reactions, of which nearly 40% were not caused by therapeutic drugs, but by drug provocation tests. The most frequent manifestations of SAD from drugs are eczematous eruptions (scattered, widespread, generalized, worsening, reactivation), maculopapular eruptions, symmetrical drug‐related intertriginous and flexural exanthema (SDRIFE [baboon syndrome]) and widespread erythema or erythroderma. Therapeutic systemic drugs hardly ever cause reactivation of previously positive patch tests and infrequently of previous allergic contact dermatitis. The pathophysiology of SAD has received very little attention. Explanations for the rarity of SAD are suggested.

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Section: Systemic Allergic Dermatitis From Systemic Drugsmentioning

confidence: 99%

“…). In those days, eczematous dermatitis from opium compounds used externally in the form of lotions, suppositories and other application forms was apparently well known 133 . A more recent review of the subject was provided in 2006 262 .…”

Section: Systemic Allergic Dermatitis From Systemic Drugsmentioning

confidence: 99%

Systemic allergic dermatitis (systemic contact dermatitis) from pharmaceutical drugs: A review

Groot¹

2021

Contact Dermatitis

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“…111 Schwartz and his associates 112 present an interesting and comprehensive paper describing an outbreak of dermatitis from the new resin fabric finishes which are found in the new wearing apparel devised in the frantic search for substitutes in this modern world. The following selections are typical.…”

Section: Hay Fevermentioning

confidence: 99%