1956
DOI: 10.1001/archderm.1956.01550030038003
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Contact Dermatitis Due to Nickel and Chromate

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1957
1957
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Cited by 64 publications
(8 citation statements)
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“…From our investigation, it is not possible to conclude which are the primary and secondary events, but most facts earlier presented indicate that nickel sensitivity followed by irritant dermatitis of the hands appears first, and that cobalt sensitivity is a secondary phenomenon (15)(16)(17). It is possible that a pre-existant nickel allergy increases the risk of developing cobalt allergy, not only because of the high frequency of hand eczema among nickel sensitive individuals but also due to unknown immunological factors (18,19). The cobalt allergy then seems to aggravate the hand eczema.…”
Section: Discussionmentioning
confidence: 61%
“…From our investigation, it is not possible to conclude which are the primary and secondary events, but most facts earlier presented indicate that nickel sensitivity followed by irritant dermatitis of the hands appears first, and that cobalt sensitivity is a secondary phenomenon (15)(16)(17). It is possible that a pre-existant nickel allergy increases the risk of developing cobalt allergy, not only because of the high frequency of hand eczema among nickel sensitive individuals but also due to unknown immunological factors (18,19). The cobalt allergy then seems to aggravate the hand eczema.…”
Section: Discussionmentioning
confidence: 61%
“…The relationship between atopy and nickel allergy is debated in several papers. Epstein (1956), Dobson (1963), Watt & Baumann (1968) found a marked positive correlation between nickel allergy and atopy whereas Calnan (1956), Wilson (1956), Marcussen (1957) and Caron (1964) found no such connection. Wahlberg & Skog (1971) found a high frequency of family atopy in relation to nickel sensitive patients.…”
Section: Discussionmentioning
confidence: 98%
“…This arouses the interesting speculation as to whether the molecular configuration of prednisolone has some special affinity for a metallic protein complex such as might be formed in chromate eczema. 5. In all four cases, after a period of complete nonexposure to chromâtes, the very marked repressive action of both hydrocortisone and prednisolone in chromate der¬ matitis was strikingly evident.…”
Section: Resultsmentioning
confidence: 82%