Contact allergy to oil of turpentine: a 10‐year retrospective view

Rudzki, E; Berova, N; Czernielewski, A; Grzywa, Z; Jirásek, E.; Kalenský, J; Michallov, P.; Nebenführer, L; Rothe, A; Schubert, H.; Szarmach, H; Temesvári, Erzsébet; Ziegler, Verena

doi:10.1111/j.1600-0536.1991.tb01743.x

Cited by 16 publications

(5 citation statements)

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“…The major contact allergen of turpentine was identified as k-3-carene hydroperoxide, an oxidation product of k-3-carene, especially in oils originating from Finland and Sweden (1,5). How- ever, patients specifically reacting to other allergens, i.e., to oxidation products of limonene, aand b-pinene, have been described (6)(7)(8)(9)(10).…”

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confidence: 99%

Increase in sensitization to oil of turpentine: recent data from a Multicenter Study on 45,005 patients from the German‐Austrian Information Network of Departments of Dermatology (IVDK)

et al. 2000

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Contact allergy to oil of turpentine was reported to have become rare. However, the evaluation of standardized data of 45,005 patients tested 1992-1997 in 30 Dermatological Centers associated with the German-Austrian Information Network of Departments of Dermatology (IVDK) showed an increase in positive patch test reactions to turpentine from 0.5% during the years 1992-1995, up to 1.7% in 1996 and 3.1% in 1997. In particular, 17,347 patients tested in 1996-1997 were evaluated in detail by comparing 431 individuals with positive patch test reactions with the rest of the group found negative to turpentine. Using the so-called MOAHLFA index, the following characteristics were shown. Turpentine allergy (a) was found to be significantly less frequent in men and in patients with occupational dermatitis, (b) showed no difference in its association with atopic dermatitis, (c) patients with turpentine allergy had significantly less symptoms of the hands, more symptoms of the legs or in the face and (d) were significantly more often aged over 60 years. Also, patients sensitized to turpentine had increased rates of additional sensitizations. The definite reason for the increase in turpentine sensitization in the population tested here is not clear. Therefore, a detailed exposure analysis is necessary; the new increase in turpentine allergies may be due to popular topical remedies or household chemicals.

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confidence: 99%

Increase in sensitization to oil of turpentine: recent data from a Multicenter Study on 45,005 patients from the German‐Austrian Information Network of Departments of Dermatology (IVDK)

et al. 2000

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“…Cases of contact allergy from turpentine have continuously been recorded. Patch testing with Scandinavian sulfate turpentine in Spain and gum turpentine (Iberian type) in Portugal in the 1980s resulted in many co‐reactions to the isolated terpenes 57,58 . The German‐Austrian Information Network of Departments of Dermatology (IVDK) has registered and evaluated patch test reactions to turpentine in consecutively tested patients with dermatitis.…”

Section: Discussionmentioning

confidence: 99%

One hundred years of allergic contact dermatitis due to oxidized terpenes: What we can learn from old research on turpentine allergy

Karlberg

Lepoittevin

2021

Contact Dermatitis

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Although in recent years the focus on sensitizing terpene oxidation products has been on oxidized limonene and linalool, the autoxidation of terpenes in relation to allergic contact dermatitis is not new and dates back to the early part of the 20th century with the use of turpentine causing occupational contact dermatitis in painters. This review is written in a way as to allow us to get closer to the work of the scientists in earlier days, to participate in the successes, and also to observe the weak points. The researchers concluded that the main culprit in Scandinavian turpentine was Δ 3 -carene hydroperoxides. This explains its high sensitizing effect compared with French turpentine which is of the Iberian type with no or only traces of Δ 3 -carene. Historical exposure to turpentine showed that ending the industrial exposure stopped the occupational skin sensitization. Patch test studies demonstrated that monoterpene hydroperoxides, far from being an obsolete source of contact allergy solely related to turpentine, is a common cause of contact allergy in the population. A hundred years of extensive chemical and clinical studies worldwide should be sufficient to meet the evidence requirement regarding allergic contact dermatitis caused by terpenes.

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“…Turpentine is a well-known agent that can produce skin symptoms due to type IV hypersensitivity reaction [1]. Although there is a number of papers describing turpentine to cause contact dermatitis, there is no well documented case of type I hypersensitivity reaction due to this agent.…”

Section: Discussionmentioning

confidence: 99%

“…Aplhapinene, delta-3-carene and turpentine peroxides are the main turpentine allergens [2]. There are many reports on contact dermatitis caused by turpentine exposure [1]. This type of allergy has been well described in painters, shoe repairers, home decorators and mechanics using impregnated soap [3][4][5] Little is know about type I hypersensitivity reactions caused by turpentine.…”

Section: Introductionmentioning

confidence: 99%

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Occupational asthma due to turpentine in art painter — case report

Dudek

Wittczak²,

Świerczyńska-Machura³

et al. 2009

International Journal of Occupational Medicine and Environmental Health

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Turpentine is a fluid obtained by distillation of wood resins containing mixture of terpens. It can act as an irritant and sensitiser. Most common health problem among workers exposed to turpentine is contact dermatitis. Little is know about turpentine to cause type I hypersensitivity reaction. We present a case of a 27-year old art painter using turpentine as a thinner for oil-based paints. She developed asthmatic reactions after 5 years of working with turpentine. A number of clinical procedures were performed, including clinical examination, routine laboratory tests, total serum IgE, skin prick tests to common aeroallergens, metal salts, oil-based paints and balsamic turpentine, resting spirometry test, histamine challenge, and a single-blind, placebo-controlled specific inhalation challenge with balsamic turpentine. Clinical findings and laboratory test results were normal but a significant bronchial hyperreactivity was found. During the specific challenge, dyspnoea and decreased forced expiratory volume (FEV 1 ) were observed in late phase of asthmatic reaction. An increased proportion of eosinophils in induced sputum could also be noted 24 h after the challenge. Positive clinical response to the specific challenge as well as the morphological changes found in induced sputum served as the basis for diagnosing occupational asthma. To our knowledge, this is the first well-documented case of turpentine-induced occupational asthma.

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Contact allergy to oil of turpentine: a 10‐year retrospective view

Cited by 16 publications

References 1 publication

Increase in sensitization to oil of turpentine: recent data from a Multicenter Study on 45,005 patients from the German‐Austrian Information Network of Departments of Dermatology (IVDK)

Increase in sensitization to oil of turpentine: recent data from a Multicenter Study on 45,005 patients from the German‐Austrian Information Network of Departments of Dermatology (IVDK)

One hundred years of allergic contact dermatitis due to oxidized terpenes: What we can learn from old research on turpentine allergy

Occupational asthma due to turpentine in art painter — case report

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