2020
DOI: 10.3844/ajisp.2020.8.18
|View full text |Cite
|
Sign up to set email alerts
|

Consumption of an Extremely Biodiverse Probiotic and a Supplement based on Microbial Chondroitin Sulfate is Associated with Very Low Serum Alpha-N-acetylgalactosaminidase (Nagalase) Activity and Decrease of C-reactive Protein Values

Abstract: We describe the case of a 57-years-old male healthy professional who added to his nutritional plan a novel, extremely biodiverse, probiotic and a supplement based on microbial chondroitin sulfate, vitamin D 3 and ultrapure phosphatidylcholine to improve his healthy life expectancy. After three months of such a nutritional regimen, serum alpha-Nacetylgalactosaminidase (nagalase) activity was 0.40 that is a value below the minimum level established for adults (normal values: 0.50-0.95 nMol/mL/min). C-reactive Pr… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

7
9
0

Year Published

2020
2020
2021
2021

Publication Types

Select...
2
2

Relationship

4
0

Authors

Journals

citations
Cited by 4 publications
(16 citation statements)
references
References 33 publications
7
9
0
Order By: Relevance
“…Reduction of serum nagalase activity is consistent with the observation that the extremely biodiverse probiotic yogurt described in this article has high Gc protein-derived Macrophage Activating Factor activity as demonstrated in recent studies (2,4). In addition to the effects on modulation of macrophage activity, it is worth noting that the probiotic yogurt used in this experience is highly fermented.…”
Section: Discussionsupporting
confidence: 90%
See 4 more Smart Citations
“…Reduction of serum nagalase activity is consistent with the observation that the extremely biodiverse probiotic yogurt described in this article has high Gc protein-derived Macrophage Activating Factor activity as demonstrated in recent studies (2,4). In addition to the effects on modulation of macrophage activity, it is worth noting that the probiotic yogurt used in this experience is highly fermented.…”
Section: Discussionsupporting
confidence: 90%
“…2). Nagalase is a marker for inflammation often found elevated in viral infections, cancer and other chronic conditions (4,11,12). These results are consistent with previous observations (3,4); we hypothesize that decrease of serum nagalase activity is due to the presence in the probiotic yogurt of high levels of naturally formed Gc protein-derived Macrophage Activating Factor that binds and neutralize nagalase (4,13)…”
Section: Serum Nagalase Activitysupporting
confidence: 92%
See 3 more Smart Citations