Constructing novel nanofibrous polyacrylonitrile (PAN)-based anion exchange membrane adsorber for protein separation

Yang, Xing; Hsia, Tina; Merenda, Andrea; Al-Attabi, Riyadh; Dumée, Ludovic F.; Thang, San H.; Kong, Lingxue

doi:10.1016/j.seppur.2021.120364

Cited by 17 publications

(8 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A magnetic stirrer is used to blend PAN (8 wt%) and DMF until PAN is totally dissolved, forming a yellowish PAN solution. The solution is kept at room temperature for six hours and an ultrasonicator is used to remove bubbles [ 30 , 31 , 32 ]. Afterwards, an electrospinning machine is used to produce PAN nanofibrous membranes with parameters: a spinning rate of 0.5 mL/h, a voltage of 15 kV, a collection distance of 15 cm, a temperature of 25–30 °C, and a relative humidity of 20%.…”

Section: Methodsmentioning

confidence: 99%

Lay-Up Compound Matrices for Application of Medical Protective Clothing: Manufacturing Techniques and Property Evaluations

et al. 2022

View full text Add to dashboard Cite

Medical protective clothing is the first line of defense for medical staff, which makes the acquisition of protection and multiple function challenging. When it comes to contagious diseases, the physical properties of protective clothing are deemed the top priority and, subsequently, they have significant meaning for the structural design, production cost evaluation, convenient production, and innovation. In this study, nonwoven technology is employed to produce matrices in which mechanical properties are supported by Tencel fibers and recycled Kevlar fibers. Next, the electrostatic spinning is conducted to generate breathable and waterproof films. The nonwoven fabrics and membranes are combined to have diverse functions, forming lay-up compound matrices for medical protective clothing. Moreover, measurements are conducted to characterize the lay-up compound matrices in terms of the tensile strength, tearing strength, bursting strength, puncture resistance, stiffness, air-permeable property, surface resistance, comfort performance, sub-micron particulate filtration efficiency, and the penetration of synthetic blood. As for the nonwoven fabrics, the mechanical properties are significantly improved after Kevlar fibers are incorporated. The tensile strength is (62.6 ± 2.4) N along the machine direction (MD) and (50.1 ± 3.1) N along the cross machine direction (CD); the tearing strength is (29.5 ± 1.6) N along the MD and (43.0 ± 1.7) N along the CD; the bursting strength is (365.8 ± 5.0) kPa; and the puncture resistance is (22.6 ± 1.0) N. Moreover, the lay-up compound matrices exhibit a stiffness of (14.7 ± 0.2) cm along the MD and (14.6 ± 0.1) cm along the CD, a surface resistance of (2.85 × 109 ± 0.37 × 109) Ω, an air-permeable property of (45.4 ± 2.3) cm3/s/cm2, and sub-micron particulate filtration efficiency of over 98%. In the measurement for penetration of synthetic blood, the K40/PAN/TPU group prevents the synthetic blood from penetration. Hence, the incorporation of recycled Kevlar fibers and lay-up compound technique creates good physical properties, an appropriate comfort attribute, and functions, which suggests that this study provides a greater diversity and new concepts for the production of medical protective clothing.

show abstract

Section: Methodsmentioning

confidence: 99%

Lay-Up Compound Matrices for Application of Medical Protective Clothing: Manufacturing Techniques and Property Evaluations

et al. 2022

View full text Add to dashboard Cite

show abstract

“…The PAN is also applied for the production of anion-exchange membranes (AEM). , Khan and Baig prepared an organic–inorganic nanocomposite AEM using a solution casting technique in various ratios of silica gel and PAN. The membrane with a composition of 1:1 silica gel/PAN presented the greatest outcomes for ion-exchange capacity, porosity, swelling, water content, and thickness.…”

Section: Application Of Pan-based Membranesmentioning

confidence: 99%

“…In another study, an electrospun PAN-based nanofiber membrane with strong anion exchange functionality was prepared thru RAFT copolymerization of dimethyl aminoethyl acrylate and acrylonitrile, followed by quaternization to create quaternary amine ligands, i.e., pAQ (Figure 9D). 96 By mixing the pAQ copolymer at different ratios, a series of pAQ/PAN nanofibrous membranes were fabricated. The obtained blend membranes presented a positive surface charge, whereas the pure PAN membrane had a negative charge.…”

Section: Pervaporationmentioning

confidence: 99%

See 1 more Smart Citation

Polyacrylonitrile in the Preparation of Separation Membranes: A Review

Vatanpour

Paşaoğlu

Köse-Mutlu

et al. 2023

Ind. Eng. Chem. Res.

View full text Add to dashboard Cite

Polyacrylonitrile (PAN) is a hydrophilic polymer with good chemical resistance, low price, and excellent processability for fabricating membranes, especially for electrospun nanofiber-based membranes. In this review, the recent developments in the application and modification of PAN membranes are discussed, focusing on some applications such as pervaporation (PV), ion exchange, hemodialysis, membrane distillation, adsorption membrane, and water and wastewater treatment. First, the physicochemical characteristics and the synthesis techniques of the PAN are discussed, and next, the PAN application in the fabrication of membrane is reviewed. Different PAN membranes with their fabrication techniques are reviewed with detailed studies focused on the modification methods. By using different modifiers especially nanomaterial blending, the physicochemical properties and performance (membrane structure, permeability, mechanical strength, hydrophilicity, porosity, and surface charge) of the PAN membranes are improved. Finally, the challenges and future perspective of these membranes are discussed. The review of research progress in this paper may provide an insight into the development of high-performance PAN membranes and spread the applications of PAN membranes in different separation processes in the future.

show abstract

“…Yang et al [ 79 ] through blending and electrospinning integrated the prefunctionalized quaternary amine PAN copolymer into the traditional PAN homopolymer, and designed an electrospun PAN-based composite membrane with a strong anion exchange function, which could be easily customized for different separation purposes. Tris(hydroxymethyl)aminomethane-functionalized electrospinning PAN nanofiber membrane prepared affinity membrane chromatography with powerful binding specificity and well adsorption ability for the corresponding target [ 80 ].…”

Section: Membrane Matrixmentioning

confidence: 99%

Recent development and application of membrane chromatography

Chen

Cong

et al. 2022

Anal Bioanal Chem

View full text Add to dashboard Cite

Membrane chromatography is mainly used for the separation and purification of proteins and biological macromolecules in the downstream processing process, also applications in sewage disposal. Membrane chromatography is recognized as an effective alternative to column chromatography because it significantly improves chromatography from affinity, hydrophobicity, and ion exchange; the development status of membrane chromatography in membrane matrix and membrane equipment is thoroughly discussed, and the applications of protein capture and intermediate purification, virus, monoclonal antibody purification, water treatment, and others are summarized. This review will provide value for the exploration and potential application of membrane chromatography. Graphical abstract

show abstract

Constructing novel nanofibrous polyacrylonitrile (PAN)-based anion exchange membrane adsorber for protein separation

Cited by 17 publications

References 33 publications

Lay-Up Compound Matrices for Application of Medical Protective Clothing: Manufacturing Techniques and Property Evaluations

Lay-Up Compound Matrices for Application of Medical Protective Clothing: Manufacturing Techniques and Property Evaluations

Polyacrylonitrile in the Preparation of Separation Membranes: A Review

Recent development and application of membrane chromatography

Contact Info

Product

Resources

About