Consensus document of the Spanish Association for Study of the Liver on the treatment of hepatitis B virus infection (2020)

Rodríguez, Manuel; Buti, María; Esteban, Rafael; Lens, Sabela; Prieto, Martín; Suárez, Emilio; García‐Samaniego, J.

doi:10.1016/j.gastre.2020.03.008

Cited by 27 publications

(26 citation statements)

References 178 publications

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“…Likewise, immune checkpoint inhibitors also carry a significant risk of HBV reactivation, which may be up to 21%, with the additional risks of autoimmune hepatitis and further immunosuppression due to frequent glucocorticoids treatment. HBV reactivation is associated with a variety of liver disease, ranging from transient asymptomatic elevation of transaminases to fulminant hepatitis and death [9,40,41]. Risk of reactivation for each specific anticancer agent has not been established.…”

Section: Hepatitis Screening For Patients With Cancer Prior To Therapymentioning

confidence: 99%

SEOM clinical guidelines for the prophylaxis of infectious diseases in cancer patients (2021)

et al. 2022

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Infections are still a major cause of morbi-mortality in patients with cancer. Some of these infections are preventable through specific measures, such as vaccination or prophylaxis. This guideline aims to summarize the evidence and recommendations for the prevention of infections in cancer patients, devoting special attention to the most prevalent preventable infectious disease. All the evidences will be graded according to The Infectious Diseases Society of America grading system.

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Section: Hepatitis Screening For Patients With Cancer Prior To Therapymentioning

confidence: 99%

SEOM clinical guidelines for the prophylaxis of infectious diseases in cancer patients (2021)

et al. 2022

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“…El resultado ideal es el aclaramiento del HBsAg (curación funcional), que se produce solo en una pequeña proporción de pacientes en tratamiento 28 . En todo caso, debe recordarse que la erradicación total de la infección no es posible, debido a la persistencia en las células del ADNccc en el núcleo de los hepatocitos 29 .…”

Section: Tratamiento De La Hcvhbunclassified

“…Los criterios terapéuticos se basan en tres parámetros: niveles de ALT, niveles de ADN-VHB y grado de lesión celular basada en biopsia hepática o en métodos no invasivos. Para prescribir tratamiento, se deben cumplir al menos dos de los tres criterios, como sería niveles ALT superiores a la normalidad, cifras de ADN-VHB >20.000U/L y/o un grado de fibrosis 2 o superior 29 .…”

Section: Tratamiento De La Hcvhbunclassified

“…La prevención primaria del CHC en los pacientes con HCVHB se basa en la vacunación antihepatitis B 29 , y la secundaria, en la prescripción de tratamiento antiviral según las recomendaciones vigentes 29,30 . El clínico puede recordar, de forma general, que en España, los nacidos antes de 1980 no están vacunados, y los nacidos entre 1980 y 1998 pueden no estarlo.…”

Section: Prevención E Indicaciones De Cribado En El Chcunclassified

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Diagnosis and treatment of hepatitis B. What contributions can prisons make?

Vergara¹

2021

Rev Esp Sanid Penit

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Hepatitis B is a parenterally and sexually transmitted infection. Vaccination for the disease is highly effective, and its inclusion in Spain as part of a systematic and universal schedule for newborns has led to a significant decrease of incidence in the national population. However, the number of inmates born in other countries - some from endemic areas of HBV infection -, the mechanisms of transmission and lack of vaccination in third world countries mean that its prevalence in the prison population is higher than in the general population. These institutions therefore play an essential role in detecting and managing hepatitis B. In this paper, the situation of hepatitis B in prisons is reviewed and recommendations are proposed to optimize its control.

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“…Patients who are HBsAg, anti-HBs, and anti-HBc negative do not possess immunity needs vaccination. Patients who are only anti-HBs-positive are immune or have undergone vaccination[98][99][100].…”

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confidence: 99%