Conocimientos y factores de riesgo relacionados con la enfermedad de Chagas en dos comunidades panameñas donde Rhodnius pallescens es el vector principal

Hurtado, Lisbeth; Calzada, José E.; Pineda, Vanessa; González, Kadir; Santamaría, Ana María; Cáceres, Lorenzo; Wald, Coridalia; Saldaña, Azäel

doi:10.7705/biomedica.v34i2.2133

Cited by 18 publications

(12 citation statements)

References 24 publications

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“…Herein, insects were found in the three ecotopes and most specimens (both nymphs and adults) were collected in sylvatic habitats mainly in wine ( A. butyracea ) and oil ( Elaeis guineensis ) palm trees, while 21.6% (adults) were collected in domestic habitats. This is consistent with previous studies in Colombia [27, 57, 58, 60, 61] and Panama [40, 58, 62–65], where the percentage of T. cruzi infection is similar to our results. Moreover, it was observed that the main feeding source was human blood across the three ecotopes.…”

Section: Discussionsupporting

confidence: 94%

Untangling the transmission dynamics of primary and secondary vectors of Trypanosoma cruzi in Colombia: parasite infection, feeding sources and discrete typing units

et al. 2016

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Background Trypanosoma cruzi is the causative agent of Chagas disease. Due to its genetic diversity has been classified into six Discrete Typing Units (DTUs) in association with transmission cycles. In Colombia, natural T. cruzi infection has been detected in 15 triatomine species. There is scarce information regarding the infection rates, DTUs and feeding preferences of secondary vectors. Therefore, the aim of this study was to determine T. cruzi infection rates, parasite DTU, ecotopes, insect stages, geographical location and bug feeding preferences across six different triatomine species.MethodsA total of 245 insects were collected in seven departments of Colombia. We conducted molecular detection and genotyping of T. cruzi with subsequent identification of food sources. The frequency of infection, DTUs, TcI genotypes and feeding sources were plotted across the six species studied. A logistic regression model risk was estimated with insects positive for T. cruzi according to demographic and eco-epidemiological characteristics.ResultsWe collected 85 specimens of Panstrongylus geniculatus, 77 Rhodnius prolixus, 37 R. pallescens, 34 Triatoma maculata, 8 R. pictipes and 4 T. dimidiata. The overall T. cruzi infection rate was 61.2% and presented statistical associations with the departments Meta (OR: 2.65; 95% CI: 1.69–4.17) and Guajira (OR: 2.13; 95% CI: 1.16–3.94); peridomestic ecotope (OR: 2.52: 95% CI: 1.62–3.93); the vector species P. geniculatus (OR: 2.40; 95% CI: 1.51–3.82) and T. maculata (OR: 2.09; 95% CI: 1.02–4.29); females (OR: 2.05; 95% CI: 1.39–3.04) and feeding on opossum (OR: 3.15; 95% CI: 1.85–11.69) and human blood (OR: 1.55; 95% CI: 1.07–2.24). Regarding the DTUs, we observed TcI (67.3%), TcII (6.7%), TcIII (8.7%), TcIV (4.0%) and TcV (6.0%). Across the samples typed as TcI, we detected TcIDom (19%) and sylvatic TcI (75%). The frequencies of feeding sources were 59.4% (human blood); 11.2% (hen); 9.6% (bat); 5.6% (opossum); 5.1% (mouse); 4.1% (dog); 3.0% (rodent); 1.0% (armadillo); and 1.0% (cow).ConclusionsNew scenarios of T. cruzi transmission caused by secondary and sylvatic vectors are considered. The findings of sylvatic DTUs from bugs collected in domestic and peridomestic ecotopes confirms the emerging transmission scenarios in Colombia.Electronic supplementary materialThe online version of this article (doi:10.1186/s13071-016-1907-5) contains supplementary material, which is available to authorized users.

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Section: Discussionsupporting

confidence: 94%

Untangling the transmission dynamics of primary and secondary vectors of Trypanosoma cruzi in Colombia: parasite infection, feeding sources and discrete typing units

et al. 2016

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“…Another triatomine species with a very high prevalence was R. pallescens with geographical predominance in the north-west part of the country (Caribbean region). This vector has been also associated with Attalea butyracea palms [63, 66–87], has been reported frequently in Costa Rica and Nicaragua [67] and it is considered the main vector in Panama [68, 69]. Importantly, this species has been found commonly circulating in areas of oral outbreaks in Colombia [37].…”

Section: Discussionmentioning

confidence: 99%

Heterogeneity of Trypanosoma cruzi infection rates in vectors and animal reservoirs in Colombia: a systematic review and meta-analysis

et al. 2019

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Background The heterogeneity of Trypanosoma cruzi infection rates among triatomines insects and animal reservoirs has been studied in independent studies, but little information has been systematised to allow pooled and comparative estimates. Unravelling the main patterns of this heterogeneity could contribute to a further understanding of T. cruzi transmission in Colombia. Methods A systematic search was conducted in PubMed, Medline, LILACS, Embase, Web of Knowledge, Google Scholar and secondary sources with no filters of language or time and until April 2018. Based on selection criteria, all relevant studies reporting T. cruzi infection rates in reservoirs or triatomines were chosen. For pooled analyses, a random effects model for binomial distribution was used. Heterogeneity among studies is reported as I 2 . Subgroup analyses included: taxonomic classification, ecotope and diagnostic methods. Publication bias and sensitivity analyses were performed. Results Overall, 39 studies reporting infection rates in Colombia were found (22 for potential reservoirs and 28 for triatomine insects) for a total sample of 22,838 potential animals and 11,307 triatomines evaluated for T. cruzi infection. We have found evidence of 38/71 different animal species as potential T. cruzi reservoirs and 14/18 species as triatomine vectors for T. cruzi . Among animals, the species with the highest pooled prevalence were opossum ( Didelphis marsupialis ) with 48.0% (95% CI: 26–71%; I 2 = 88%, τ 2 = 0.07, P < 0.01) and domestic dog ( Canis lupus familiaris ) with 22.0% (95% CI: 4–48%; I 2 = 96%, τ 2 = 0.01, P < 0.01). Among triatomines, the highest prevalence was found for Triatoma maculata in the peridomestic ecotope (68.0%, 95% CI: 62–74%; I 2 = 0%, τ 2 = 0, P < 0.0001), followed by Rhodnius prolixus (62.0%, 95% CI: 38–84%; I 2 = 95%, τ 2 = 0.05, P < 0.01) and Rhodnius pallescens (54.0%, 95% CI: 37–71%; I 2 = 86%, τ 2 = 0.035, P < 0.01) in the sylvatic ecotope. Conclusions To our knowledge, this is the first systematic and quantitative analyses of triatomi...

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“…La extensión del área endémica, la variedad de vectores con comportamientos diversos y las múltiples variables que intervienen y determinan diferentes patrones de transmisión, revelan la necesidad imperiosa de adoptar un manejo del riesgo y del control vectorial específicos en cada zona (14)(15)(16).…”

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Risk of transmission of Chagas disease by intrusion of triatomines and wild mammals in Bucaramanga, Santander, Colombia

et al. 2017

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Introducción. La notificación de triatominos en las viviendas de algunos barrios de Bucaramanga motivó la realización de este estudio.Objetivo. Evaluar la intrusión de triatominos y mamíferos, así como algunos factores de riesgo para la enfermedad de Chagas en viviendas urbanas.Materiales y métodos. En un barrio de Bucaramanga, Santander, se recolectaron triatominos mensualmente durante un año con participación comunitaria mediante búsqueda manual en el alumbrado público, y el uso de trampas de luz, cebo animal y atrayentes químicos en el bosque cercano. Los reservorios se recolectaron con trampas cebadas. Los insectos y mamíferos se determinaron y examinaron para establecer su infección natural. Los factores de riesgo de las viviendas se midieron mediante una encuesta sobre factores sociales y ambientales.Resultados. Se recolectaron 11 adultos de Panstrongylus geniculatus y 63 de Rhodnius pallescens en el bosque, en zonas de recreación en el peridomicilio y en el domicilio, incluidas dos hembras y 21 ninfas de R. pallescens en dormitorios. Se capturaron dos ejemplares de Didelphis marsupialis en el bosques adyacente. De los 11 individuos de P. geniculatus capturados, se examinaron nueve, de los cuales cinco fueron positivos para Trypanosoma cruzi (56 %); de los 63 individuos de R. pallescens capturados, se examinaron ocho, cuatro de los cuales fueron positivos para T. cruzi (50 %). De dos especímenes de D. marsupiales capturados, uno fue examinado y se encontró que era positivo para T. cruzi. No se pudo establecer un factor de riesgo significativo, sin embargo, las viviendas con reporte de triatominos se encontraban más cerca del bosque adyacente.Conclusiones. El hallazgo de especies de triatominos intrusivas y de mamíferos con T. cruzi en el domicilio y el peridomicilio, así como en los bosques periurbanos, demuestra el riesgo de infección en las poblaciones que habitan en viviendas urbanas adyacentes a los ecótopos donde se mantiene el ciclo silvestre.

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Conocimientos y factores de riesgo relacionados con la enfermedad de Chagas en dos comunidades panameñas donde Rhodnius pallescens es el vector principal

Cited by 18 publications

References 24 publications

Untangling the transmission dynamics of primary and secondary vectors of Trypanosoma cruzi in Colombia: parasite infection, feeding sources and discrete typing units

Untangling the transmission dynamics of primary and secondary vectors of Trypanosoma cruzi in Colombia: parasite infection, feeding sources and discrete typing units

Heterogeneity of Trypanosoma cruzi infection rates in vectors and animal reservoirs in Colombia: a systematic review and meta-analysis

Risk of transmission of Chagas disease by intrusion of triatomines and wild mammals in Bucaramanga, Santander, Colombia

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