Connective tissue: Vascular and hematological (blood) support

Abstract

Connective Tissue (CT) is a ubiquitous component of all major tissues and structures of the body (50% of all body protein is CT), including that of the blood, vascular, muscle, tendon, ligament, fascia, bone, joint, IVD's (intervertebral discs) (eg, muscles, tendons, ligaments, fascia, bone, and joints), integument (skin) and inflammatory and immune mediation will be discussed here and will deal with connective tissue dynamics and dysfunction. An overview of the current scientific understanding and possible options for naturally enhancing the structure and function of CT through the application of these concepts will be discussed in this article, with specific attention on the vascular and hematological systems. (J Chiropr Med 2003;2:25-36)

Ascorbate promotes carbon tetrachloride-induced hepatic injury in senescence marker protein 30-deficient mice by enhancing inflammation

“…Hepatic fibrosis results in the excessive deposition of collagen type I, and ascorbate, as a cofactor of prolyl hydroxylase, is integral in this process [33]. Therefore, ascorbate deficiency may, in part, delay fibrogenesis in SMP30 −/− mice by destabilization of collagen fiber.…”

Assessment of Prevalence of Dyslipidemia and to Evaluate the Role of Corticosteroids among Patients with Connective Tissue Disorder: Prospective Clinical Study

“…These tissues form a framework, or matrix, for the body, and are composed of two major structural protein molecules which are collagen and elastin. 1 Dyslipidemia is elevation of plasma cholesterol, triglycerides (TGs), or both, or a low HDL cholesterol level that contributes to the development of atherosclerosis. Atherosclerosis and cardiovascular disease risk is enhanced in certain connective tissue diseases such as Systemic lupus erythematosus, Rheumatoid arthritis, Sjogren's syndrome, and mixed connective tissue disorders.…”