Connection between the physicochemical properties of benzimidazoles and their efficacy againstNippostrongyliasis in mice

Synthesis, Characterization and Antimicrobial Activity of d8-10 MetalComplexes of some 2‐Substituted‐1H‐Benzimidazoles

“…Nine 2-substituted-lH-benzimidazole derivatives (I-IX) (Figures and 2) and their 74 complexes formed by reactions with NiCI2, PdCI2, Pd(NO3)2, CuCl2, Cu(CH3COO)2, Cu(CIO4)2, AgNO3, ZnCI2, ZnSO4 have been isolated in pure form for first time and characterized by using analytical data and IR spectroscopy. The compounds i-IV, VIII and IX have variously biological activities, which are antinematodic [10], fungicide [ 11], antelmintic [ 12], sedative [ 13] and antipoliovirus [ 14] for I, antifungal [ 15], antinematodic [10,16], antelmintic [17], tuberculostatic [18] and antiinflammatory [19] for If, antiinflammatory [20] for 111, antifungal [15], nematocide [21], tuberculostatic [ 18] and antelmintic [17,22] for IV, antipoliovirus [23] and antifungal[24] for VIII. The compound IX decreased the yield of intracellular virus [25].…”