Conjunctival changes following Muller’s muscle conjunctival resection

Beaulieu, Robert; McDonnell, Emma C.; Scofield-Kaplan, Stacy M.; Evers, B. Mark; Hogan, R. Nick; Mancini, Ronald

doi:10.1007/s10792-021-02163-8

Cited by 5 publications

(2 citation statements)

References 17 publications

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“…One issue with conjunctivo-mullerectomy is that its posterior approach may worsen dry eyes by damaging the otherwise healthy conjunctiva or accessory lacrimal gland 22,23 . Evidence supporting this concern has been provided by Beaulieu et al 24 , who reported that there was goblet cell depletion in the conjunctiva overlying the region of surgery. However, Bruna et al 25 found that combining conjunctivomullerectomy with upper eyelid blepharoplasty did not worsen ocular surface scores or dry eye symptoms.…”

Section: Discussionmentioning

confidence: 89%

Comparison of Clinical Outcomes of Conjunctivo-Mullerectomy for Varying Degrees of Ptosis

Pornpanich,

Shanokprasith,

Jaru-ampornpan

et al. 2023

Preprint

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To compare the success of conjunctivo-mullerectomy in patients with varying degrees of ptosis and identify factors affecting outcomes and complications. The Prospective cohort was studied in patients with ptosis undergoing conjunctivo-mullerectomy with or without tarsectomy were enrolled. Ptosis was classified as mild, moderate, and severe per margin-to-reflex distance 1 (MRD1). Postoperative MRD1, complications, and 3-month success rates were evaluated.The study enrolled 258 ptotic eyes of 159 patients. Most eyes (233; 90.3%) achieved surgical success, 14 (5.4%) were overcorrected, and 11 (4.3%) were undercorrected. The success rates for mild, moderate, and severe ptosis were 96.6%, 91.7%, and 83.5%, respectively. The mild and moderate ptosis groups had a nonsignificant difference in success (-4.9%; 95% CI, -12.0–4.5%; P = 0.36). However, the mild and severe ptosis groups’ rates significantly differed (-13.1%; 95% CI, -23.6% to -1.9%; P = 0.03). For all 3 ptosis groups, the success rates of individuals undergoing surgery without tarsectomy did not significantly differ. Patients undergoing conjunctivo-mullerectomy with tarsectomy had an increased risk of unsuccessful surgery (OR 3.103; 95% CI, 1.205–7.986; P = 0.019). In conclusions, Conjunctivo-mullerectomy is safe and effective for all ptosis severities. The success rate was significantly lower for severe ptosis than mild or moderate ptosis. Levator muscle function was not associated with unsuccessful outcomes, but tarsectomy was.

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Section: Discussionmentioning

confidence: 89%

Comparison of Clinical Outcomes of Conjunctivo-Mullerectomy for Varying Degrees of Ptosis

Pornpanich,

Shanokprasith,

Jaru-ampornpan

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

“…One issue with conjunctivo-mullerectomy is that its posterior approach may worsen dry eyes by damaging the otherwise healthy conjunctiva or accessory lacrimal gland 24 , 25 . Evidence supporting this concern has been provided by Beaulieu et al 26 , who reported that there was goblet cell depletion in the conjunctiva overlying the region of surgery. However, Bruna et al 27 found that combining conjunctivo-mullerectomy with upper eyelid blepharoplasty did not worsen ocular surface scores or dry eye symptoms.…”

Section: Discussionmentioning

confidence: 89%

Comparison of clinical outcomes of conjunctivo-mullerectomy for varying degrees of ptosis

Pornpanich,

Shanokprasith,

Jaru-ampornpan

et al. 2023

Sci Rep

View full text Add to dashboard Cite

To compare the success of conjunctivo-mullerectomy in patients with varying degrees of ptosis and identify factors affecting outcomes and complications. The prospective cohort was studied in patients with ptosis undergoing conjunctivo-mullerectomy with or without tarsectomy were enrolled. Ptosis was classified as mild, moderate, and severe per margin-to-reflex distance 1 (MRD1). Postoperative MRD1, complications, and 3-month success rates were evaluated. The study enrolled 258 ptotic eyes of 159 patients. Most eyes (233; 90.3%) achieved surgical success, 14 (5.4%) were overcorrected, and 11 (4.3%) were undercorrected. The success rates for mild, moderate, and severe ptosis were 96.6%, 91.7%, and 83.5%, respectively. The mild and moderate ptosis groups had a nonsignificant difference in success (− 4.9%; 95% CI − 12.0% to 4.5%; P = 0.36). However, the mild and severe ptosis groups’ rates significantly differed (− 13.1%; 95% CI − 23.6% to − 1.9%; P = 0.03). For all 3 ptosis groups, the success rates of individuals undergoing surgery without tarsectomy did not significantly differ. Patients undergoing conjunctivo-mullerectomy with tarsectomy had an increased risk of unsuccessful surgery (OR 3.103; 95% CI 1.205–7.986; P = 0.019). In conclusions, Conjunctivo-mullerectomy is safe and effective for all ptosis severities. The success rate was significantly lower for severe ptosis than mild or moderate ptosis. Levator muscle function was not associated with unsuccessful outcomes, but tarsectomy was.

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Sutureless Conjunctiva-Sparing Posterior Ptosis Repair Surgery: A Novel Technique

Mancini¹,

Forouzan²,

Keenum³

et al. 2023

American Journal of Ophthalmology

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Conjunctival changes following Muller’s muscle conjunctival resection

Cited by 5 publications

References 17 publications

Comparison of Clinical Outcomes of Conjunctivo-Mullerectomy for Varying Degrees of Ptosis

Comparison of Clinical Outcomes of Conjunctivo-Mullerectomy for Varying Degrees of Ptosis

Comparison of clinical outcomes of conjunctivo-mullerectomy for varying degrees of ptosis

Sutureless Conjunctiva-Sparing Posterior Ptosis Repair Surgery: A Novel Technique

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