Congenital primary milium of the nipple

Congenital Milium of the Nipple

“…Pearls in the areola are frequent, but involvement of the nipple seems to be rare. We found three published cases of milia in the nipple and only one was congenital (Table ) .…”

“…The differential diagnosis of a solitary pearl in the nipple included milia, syringoma with milia‐like structures, trichoepithelioma, fibroma, milia‐like idiopathic calcinosis cutis, and neonatal fibroadnexal polyp . Only milia and fibroadnexal polyp could be congenital, both are common and autolimited . The absence of a pedicle, typical of fibroadnexal polyp, justified our “wait and see” approach, as we chose not to perform a biopsy and histologic study of the girl's nipple.…”

Congenital Primary Milium on Nipple in a 3 Month Old Female Infant

“…Milia are tiny sub epidermal keratin cysts of usually 1-2 mm in diameter, contains lamellated keratins and present as pearly white or whitish-yellow domed papules [1]. Milia may be primary, probably resulting from the embryonic abnormality in the epithelial bud, or secondary originating from the damaged eccrine ducts or pilosebaceous units [2]. Onset of primary milia may be congenital or after birth.…”

“…Onset of primary milia may be congenital or after birth. These appear spontaneously and of note, spontaneous resolution of congenital forms may also occur mostly during the fourth week of life [2]. Congenital primary milia are seen to occur in up to 50% of full-term neonates, predominantly affecting nose, infraorbital and periocular skin [3].…”

“…Congenital primary milia are seen to occur in up to 50% of full-term neonates, predominantly affecting nose, infraorbital and periocular skin [3]. Uncommonly, solitary larger milium may occur on the penis, scrotum, areola and vulva [2,3].…”