Congenital Panfollicular Nevus in a 6‐Month‐Old Girl

Abstract

A 6-month-old girl presented with an irregular nodule on the right lateral neck. The lesion, which superficially resembled a lymphangioma or mastocytoma, had been present since birth but had recently been growing. The patient was referred for surgical resection. Microscopic findings were compatible with a recently described rare hamartoma termed "panfollicular nevus," which is a well-circumscribed lesion containing aberrantly differentiated, clustered hair follicles in high density.

Paediatric cutaneous adnexal tumours: a study of 559 cases

“…Early presentation and the presence of malformed hair follicles representing all stages of follicular development are characteristic of this lesion. [18][19][20] It is possible that this entity is not as uncommon as might be inferred from the rarity of reports in the literature, and review of additional series of lesions reported as appendageal tumours or naevus sebaceus in infants may reveal additional cases.…”

Case of congenital panfollicular nevus with remarkable adipose tissue proliferation

“…There have been only three cases of CPN reported in the published work to date. These cases showed slightly pink, oval, hairless, multinodular protuberances of 2.1-5.5 cm on the neck 1,4 or on the hand and wrist. 5 The clinical features of our case were very similar in terms of size, shape and color to those of the previous reports; however, the lesion in our case was elevated.…”