Congenital orbital teratoma: A review and report of two cases

Antenatally diagnosed congenital orbital teratoma in which rupture was associated with intrauterine fetal death

“…Fetuses with sacrococcygeal teratoma (SCT) have a high risk of perinatal complications and death. [3][4][5][6][7][8][9][10][11][12][13][14][15] Tumor rupture may occur during labor, particularly if the delivery is uncontrolled; therefore, in some cases with a large extracranial mass, as in our case, cesarean delivery could be considered. Indeed we have previously reported a case of a fetus with a SCT that developed severe anemia following spontaneous rupture of the tumor in utero.…”

“…1,7,8 Additionally, some intracranial teratomas will have secondary orbital extension, which will induce rapid polyhydramnios or hydrocephalus. 1,9,10 Since intracranial extension is important for prognosis, 1,11,12 MRI results may direct prenatal counseling. In our case, the mass found on MRI was limited to the orbit with no intracranial or scalp extension and the tumor was easily separated from the orbit at autopsy.…”

Congenital orbital teratoma presenting as microphthalmos with cyst

“…Extreme proptosis at birth, coupled with a developmentally intact globe and an orbital mass having a variegated appearance and consistency, is essentially diagnostic of primary orbital teratoma. [5] Clinically it is difficult to distinguish other benign and malignant neoplasms from teratoma. The differential diagnoses for cystic anomalies include microphthalmia with cyst, congenital cystic eye, microphthalmia with cystic teratoma, ectopic brain tissue and meningoencephalocele.…”

Teratom der Schädelbasis bei einem Neugeborenen: Verlaufsbeschreibung einer interdisziplinären Behandlung

“…Die Prognose für ein Neugeborenes mit einem oropharyngeal-intrakraniellen gewachsenen Teratom ist ausgesprochen schlecht. Unter den 24 Fällen, die aus der Literatur bekannt sind [1, 5 ± 7, 9, 10, 12, 14, 15, 18, 20 ± 23, 26 ± 30], verstarben 9 Kinder unmittelbar post partum oder wurden bereits tot geboren [5,6,10,15,20,23,27]. Ein Überleben von mehreren Jahren nach operativer Entfernung eines oropharyngeal-intrakraniellen Teratoms ist nur in 7 Fällen dokumentiert [1,7,12,14,18,26].…”

“…Folge haben [5,6,10,15,20,23,27]. Eine potenziell letale Komplikation lebend geborener Säuglinge mit oropharyngealen Teratomen besteht in der Verlegung der Atemwege des Neugeborenen unmittelbar post partal.…”