Congenital Malaria and Pregnancy Monitoring Parameters in Health Facilities in Guinea

Abstract

Malaria is much more common in pregnant women, especially during the third trimester of pregnancy, causing congenital infestation. Acute and severe complications are noted, including malignant malaria access and maternal and fetal mortality. Method: This was a three-month descriptive and analytical multicenter study, running from 1st January to 31st March 2015, conducted in 16 maternity hospitals at different levels of the health system pyramid. Results: Out of a total of 1772 mothers recruited for this study, 276 cases were tested positive (umbilical cordon and newborn's heel). Among them, we reported 130 cases tested positive at newborn's heel with congenital infestation confirmed by sampling on day 0, with a frequency of 7.3%. The average age of the mothers was 26 ± 14 years. With a predominance in the 20-35 age group (4.7%). Among mothers who were not exposed to preventive intermittent sulfadoxine pyrimethamine (IPT/SP) in malaria prevention, 6.1% of newborns tested positive. Of these, mothers who had less than 4 prenatal visits during pregnancy had a congenital malaria rate of 7.3%. Conclusion: Congenital malaria infestation exists in newborns despite adequate measures used in pregnant women (SP, antimalarial drugs). In Guinea, It is often found in newborns of mothers who suffer from malaria during pregnancy and whose prenatal cares are not regular.

Prevalence of Congenital Malaria in Kisangani, A Stable Malaria Transmission Area in Democratic Republic of the Congo

“…Our result is lower than that of Bah et al [19] who found a prevalence of congenital malaria of 15.57% in Guinea. In addition to the TDS in cord blood and placenta, like in ours, these authors also took into account the TDS in the heel to define the case of congenital malaria.…”

“…In our research, 92.31% of newborns with congenital malaria were born from mothers who completed ANC. This result does not agree with Bah et al [19] who had diagnosed congenital malaria in 7.3% of newborns of mothers with at least 4 CPN.…”

“…As for age, our result is similar to that found by Noudamadjo et al [23] who found that the age of newborns' mothers with congenital malaria was less than 30 years in 78.9% of cases and between 20 and 30 years in 66.7% of cases. Bah et al [19] found an average age of newborns' mothers with congenital malaria of 26 ± 14 years with prevalence in the age group of 20-35 years (4.7%) while Agossou et al [24] had found an average age of 27:3 ± 6 years with extremes of 15 to 42 years. Vanga-Bosson et al [25] found a median of 17 years.…”