Congenital clinical malaria: Incidence, management and outcome as seen in the Usmanu Danfodiyo Univrsity Teaching Hospital, Sokoto in Nigeria

Onankpa, BO; Nm, Jiya; Achegbulu, P; Airede, K I

doi:10.4314/smj2.v10i1.12926

Cited by 4 publications

(10 citation statements)

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“…The low parasitaemia rate and zero mortality recorded against malaria-infected babies in this study, which have also been reported by some other authors [11,23], could confirm that maternal antibodies still convey some protection against parasite multiplication and progression of disease and so reduces the risk of severe malaria in this group of patients [24]. However, bearing in mind the potential fatality of the P. falciparum specie, there is a call for greater concern for early and accurate diagnosis as well as appropriate case management to avoid undue morbidity and potential mortality.…”

Section: Discussionsupporting

confidence: 73%

Plasmodium falciparum infection among neonates in the North Central Region of Nigeria

Okoli

Okolo

Collins

2013

J Infect Dev Ctries

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Introduction: This cross-sectional study investigated the rate of congenital and neonatal malaria infections in patients attending our hospital. Methodology: Thick and thin blood films of 288 neonates admitted in the Special Care Baby Unit of Jos University Teaching Hospital, Nigeria, were examined microscopically for malaria parasites. Babies' and mothers' demographic and clinical data were analyzed. Results: Of 288 blood samples examined, 160 (55.6%) were from males, 115 (39.9%) were from babies 0 to 7 days old, and 173 (60.1%) were from babies 8 to 28 days old. In total, 91 (31.6%) babies had malaria parasitaemia, of whom 49 (53.8%) were males. Malaria was significantly higher in babies 8 to 28 days old (p<0.001) and was independent of gender (p=0.692). Prevalence rates for congenital and neonatal malaria were 6.9% and 24.7% respectively. Clinical presentations on admission included fever, cough, pallor, jaundice, and inability to suck. A total of 145 (50.3%) babies had symptoms of malaria, of whom 56 (61.5%) had malaria parasitaemia. Symptoms of malaria were present in 35 (12.2%) babies of 59 (20.5%) mothers who had symptoms of malaria during pregnancy. Ten (11.0%) of these neonates had malaria parasitaemia, of whom 4 (0.4%) were 0 to -7days old. Plasmodium falciparum was the only specie identified. No mortality was recorded against malaria-infected babies. Conclusion: High prevalence of malaria in these neonates calls for high index of suspicion. Inclusion of malaria parasite test in the routine battery of tests for babies presenting with clinical signs and symptoms of neonatal infections is recommended.

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Section: Discussionsupporting

confidence: 73%

Plasmodium falciparum infection among neonates in the North Central Region of Nigeria

Okoli

Okolo

Collins

2013

J Infect Dev Ctries

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“…Plasmodium Sp falciparum was the only specie documented in the present study as observed by other researchers in Nigeria [18,20,21] and the Gambia [19]. This is however contrary to the study in Pakistan [22] which documented P. vivax as the commonest specie in neonates with acquired neonatal malaria.…”

Section: Discussioncontrasting

confidence: 57%

“…It is however interesting to know that previous studies have documented fever as the commonest clinical feature in neonates with positive malaria parasite [19][20][21]23]. The other clinical features observed in febrile neonates with positive malaria parasite in the present study were poor suck and jaundice.…”

Section: Discussioncontrasting

confidence: 45%

“…This was also observed in other centres in Nigeria [15,[2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21]. The increase in the frequency of congenital malaria could be due to the growing trend of resistance of P. falciparum to anti malarial drugs resulting in increased parasitaemia, increased virulence of the parasite and reduced transmission of antibody from mother to child [2,4,5].…”

Section: Discussionmentioning

confidence: 77%

“…This could be due to the poor hygienic conditions usually observed in the urban areas as compared to the rural areas [21].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Prevalence of Malaria among Neonates Presenting with Fever in Port Harcourt, Nigeria

Opara¹

2017

NCP

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Observation of Blood Donor-Recipient Malaria Parasitaemia Patterns in a Malaria Endemic Region

Faruk

Ogunrinde

Mamman

2017

Journal of Tropical Medicine

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Background Asymptomatic malaria parasitaemia has been documented in donor blood in West Africa. However, donated blood is not routinely screened for malaria parasites (MPs). The present study therefore aimed to document the frequency of blood transfusion-induced donor-recipient malaria parasitaemia patterns, in children receiving blood transfusion in a tertiary health-centre. Methodology A cross-sectional, observational study involving 140 children receiving blood transfusion was carried out. Blood donor units and patients' blood samples were obtained, for the determination of malaria parasites (MPs). Giemsa staining technique was used to determine the presence of malaria parasitaemia. Results Malaria parasites were detected in 7% of donor blood and in 8.3% of the recipients' pretransfusion blood. The incidence of posttransfusion MPs was 3%, but none of these were consistent with blood transfusion-induced malaria, as no child with posttransfusion parasitaemia was transfused with parasitized donor blood. Majority of the blood transfusions (89.4%) had no MPs in either donors or recipients, while 6.8% had MPs in both donors and recipients, with the remaining 3.8% showing MPs in recipients alone. Conclusion In conclusion, the incidence of posttransfusion malaria parasitaemia appears low under the prevailing circumstances.

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Congenital clinical malaria: Incidence, management and outcome as seen in the Usmanu Danfodiyo Univrsity Teaching Hospital, Sokoto in Nigeria

Cited by 4 publications

References 0 publications

Plasmodium falciparum infection among neonates in the North Central Region of Nigeria

Plasmodium falciparum infection among neonates in the North Central Region of Nigeria

Prevalence of Malaria among Neonates Presenting with Fever in Port Harcourt, Nigeria

Observation of Blood Donor-Recipient Malaria Parasitaemia Patterns in a Malaria Endemic Region

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