Conformational analysis, vibrational and NMR spectroscopic study of the methanesulfonamide-N,N′-1,2-ethanediylbis

Alyar, Hamit; Ünal, Arslan; Özbek, Neslihan; Alyar, Saliha; Karacan, Nurcan

doi:10.1016/j.saa.2012.01.065

Cited by 25 publications

(7 citation statements)

References 39 publications

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“…The molecular structure of the complexes with the atomic numbering scheme is shown in Figures 1-4. The crystallographic parameters, data collection, and refinement data for the complexes are given in Table 1 (8) 1-x, 1-y, -z, 2 1-x, -y, -z, 3 -x, 1-y, -z, 4 2-x, -y, -z; 5 1-x, -y, 1-z.…”

Section: Single-crystal X-ray Diffraction Data Collectionmentioning

confidence: 99%

“…The agar well diffusion method was used for the determination of antimicrobial activity of the synthesized compounds against three fungal and three bacterial strains 1 -x, 1-y, -z, 2 1-x, -y, -z, 3 -x, 1-y, -z, 4 2-x, -y, -z.…”

Section: Antimicrobial Activitymentioning

confidence: 99%

“…Although a large number of antimicrobial drugs are existing commercially, the requirement for more effective ones continues to exist, because the most common bacteria are resistant to available drugs [3]. Due to their significant pharmacology applications and widespread use in medicine, these compounds have gained importance in bioinorganic and metal-based drug chemistry [4,5]. To find better compounds, some metal sulphonamides have attracted much attention due to the fact that the complexes showed more activity than both free ligands and the corresponding metallic salts [6].…”

Section: Introductionmentioning

confidence: 99%

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Synthesis, crystal structures and antimicrobial activity of palladium metal complexes of sulfonyl hydrazone ligands

Tadavi¹,

Bendre

Patil

et al. 2020

Eur J Chem

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Palladium complexes of sulfonyl hydrazone based ligands have been prepared by refluxing with the corresponding ligands and Pd(II) salt in 2:1 ratio. The compounds have been characterized by FT-IR and UV-Vis spectroscopic methods. The crystal structure of the prepared palladium complexes has been determined by single-crystal X-ray crystallographic technique. Crystal data for C40H50N4O6PdS2 (PMHT-Pd(II) complex): triclinic, space group P-1 (no. 2), a = 7.1561(6) Å, b = 12.1300(11) Å, c = 12.6117(17) Å, α = 63.498(11)°, β = 86.694(9)°, γ = 81.451(7)° and Z = 1. The final R1 was 0.0699 (I > 2σ(I)) and wR2 was 0.1834 (all data). Crystal data for C36H42N4O6PdS2 (PTHC-Pd(II) complex): monoclinic, space group P21/n (no. 14), a = 8.6726(2) Å, b = 20.8824(4) Å, c = 10.3351(2) Å, β = 104.429(2)° and Z = 2. The final R1 was 0.0344 (I > 2σ(I)) and wR2 was 0.0840 (all data). Crystal data for C36H42N4O6PdS2 (PTHT-Pd(II) complex): monoclinic, space group P21/n (no. 14), a = 9.7658(2) Å, b = 10.0488(3) Å, c = 18.7714(4) Å, β = 99.602(2)° and Z = 2. The final R1 was 0.0334 (I > 2σ(I)) and wR2 was 0.0832 (all data). Crystal data for C40H50N4O6PdS2 (PMHC-Pd(II) complex): triclinic, space group P-1 (no. 2), a = 10.2070(9) Å, b = 12.1841(13) Å, c = 16.8879(19) Å, α = 109.005(6)°, β = 90.061(5)°, γ = 99.032(5)° and Z = 2. The final R1 was 0.0822 (I > 2σ(I)) and wR2 was 0.2293 (all data). The single-crystal structure data showed a good agreement with the experimental results. The synthesized complexes were screened for their in vitro antibacterial activity against one Gram-negative (Escherichia coli) and two Gram-positive (Bacillus subtilis and Staphylococcus aureus) bacterial strains and for in vitro antifungal activity against Aspergillus niger, Aspergillus flavus and Aspergillus fumigatus. The PTHC-Pd(II) complex possesses the nearby significant antifungal activity analogous to the standard drug fluconazole against selected fungal strains Aspergillus niger, Aspergillus Flavus and Aspergillus fumigatus as well as the same complex showed the antibacterial activity for Staphylococcus aureus as comparable to standard ofloxacin drug.

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Section: Single-crystal X-ray Diffraction Data Collectionmentioning

confidence: 99%

Section: Antimicrobial Activitymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Synthesis, crystal structures and antimicrobial activity of palladium metal complexes of sulfonyl hydrazone ligands

Tadavi¹,

Bendre

Patil

et al. 2020

Eur J Chem

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“…Molecular geometry optimizations, geometrical parameters such as bond lenghts, bond angles and torsion angles and electronic parameters consist of HOMO-LUMO energies were examined with Becke'sthree-parameterexchange functional [25] in combination with the LeeYang-Parrcorrelation functional (B3LYP) [26] density functional theory (DFT) M A N U S C R I P T A C C E P T E D ACCEPTED MANUSCRIPT method with 6-311G (d,p) basis set by using the Gaussian 09 program package [27,28]. NMR chemical shifts were calculated by DFT/B3LYP/6-311++G(2d,2p) method.…”

Section: Computational Sectionmentioning

confidence: 99%

Alkyl sulfonic acide hydrazides: Synthesis, characterization, computational studies and anticancer, antibacterial, anticarbonic anhydrase II (hCA II) activities

Özdemir

İlbiz

Gündüzalp

et al. 2015

Journal of Molecular Structure

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“…For analogous disulfonamide compounds, see: Al-Dajani et al (2011a,b). For other analyses and properties of disulfonamide compounds, see: Alyar et al (2011Alyar et al ( , 2012. For their biological and pharmaceutical activity, see: Sahu et al (2007); Innocenti et al (2008).…”

Section: Related Literaturementioning

confidence: 99%

N,N′-(Ethane-1,2-diyl)bis(methanesulfonamide)

2014

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Conformational analysis, vibrational and NMR spectroscopic study of the methanesulfonamide-N,N′-1,2-ethanediylbis

Cited by 25 publications

References 39 publications

Synthesis, crystal structures and antimicrobial activity of palladium metal complexes of sulfonyl hydrazone ligands

Synthesis, crystal structures and antimicrobial activity of palladium metal complexes of sulfonyl hydrazone ligands

Alkyl sulfonic acide hydrazides: Synthesis, characterization, computational studies and anticancer, antibacterial, anticarbonic anhydrase II (hCA II) activities

N,N′-(Ethane-1,2-diyl)bis(methanesulfonamide)

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