2001
DOI: 10.1039/b006469f
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Conformation and tautomerism of hypocrellins. Revised structure of shiraiachrome A

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Cited by 23 publications
(38 citation statements)
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References 12 publications
(11 reference statements)
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“…+++ +++ ++ ++ +++ + --: no activity (<10 mm); +: activity (10-15 mm); ++: good activity (15-20 mm); +++: very good activity (>20 mm) (Mazzini et al, 2001;Tong et al, 2004;Chen et al, 2005). Hypocrellins, as dominant compounds, were extracted from S. bambusicola (Wan and Chen, 1981), and have attracted a great deal of attention because of their lightinduced antifungal, antiviral and antitumor activity, especially against the human immunodeficiency virus (HIV) (Kocisova et al, 1999;Wang et al, 1999;Mirossay et al, 2000;Xu et al, 2001;Yang et al, 2001;Ali and Olivo, 2002;Deininger et al, 2002;Zhou et al, 2003;Chin et al, 2004).…”
Section: S T a P H Y L O C O C C U S Aureus B A Ci L L U S Subtilis Lmentioning
confidence: 94%
“…+++ +++ ++ ++ +++ + --: no activity (<10 mm); +: activity (10-15 mm); ++: good activity (15-20 mm); +++: very good activity (>20 mm) (Mazzini et al, 2001;Tong et al, 2004;Chen et al, 2005). Hypocrellins, as dominant compounds, were extracted from S. bambusicola (Wan and Chen, 1981), and have attracted a great deal of attention because of their lightinduced antifungal, antiviral and antitumor activity, especially against the human immunodeficiency virus (HIV) (Kocisova et al, 1999;Wang et al, 1999;Mirossay et al, 2000;Xu et al, 2001;Yang et al, 2001;Ali and Olivo, 2002;Deininger et al, 2002;Zhou et al, 2003;Chin et al, 2004).…”
Section: S T a P H Y L O C O C C U S Aureus B A Ci L L U S Subtilis Lmentioning
confidence: 94%
“…The helical chirality of 94 is needed to direct the stereochemistry of the aldol cyclization, but following formation of the seven-membered ring, the integrity of the helical axis is lost due to the rapid atropisomerization of 73 (4:1, P : M ) at room temperature (Scheme 21). 56…”
Section: Applications In Total Synthesismentioning
confidence: 99%
“…The stroma of this species has been used as a traditional medicine in China (Cheng et al 2004). To date, extensive studies have been conducted on compounds of S. bambusicola, which have been found to be involved in antitumor activity and antiangiogenesis (Mazzini et al 2001;Tong et al 2004;Chen et al 2005). The products, which were characterized by the name hypocrellins, form perylenequinone pigments.…”
mentioning
confidence: 99%