Conformation and Stereodynamics of Aliphatic Triisopropylsilanes in Solution and in the Solid State

The Tricarbonylchromium Complex of a Trimethyltin-SubstitutedN-(Triisopropylsilyl)indole − A Dynamic NMR Study of Multiple Independent Rotation Processes in the Solid State with an X-ray Diffraction Structure and Molecular Mechanics Calculations

“…There has already been some exploration,7−11 of the conformational possibilities for three isopropyl or similar groups attached to a tetrahedral atom, including triisopropylsilyl groups 10,11. The most recent report11 includes results both in solution and the solid state for compound 13 with a TIPS group attached to the 1‐position in naphthalene.…”

“…In view of the results in Table 3 for calculated barriers to trimethylstannyl group rotation, it is of interest to know the difference in N ‐TIPS rotation barriers to be expected when the 1‐naphthyl group of 13 is replaced by the N ‐indolyl group of 1 . Calculation of TiPSi rotational barriers is complicated, however, as one torsion usually entrains another 10. We therefore calculated the barrier to a simplified 120° rotation about the peri bond for 13 and for N ‐TIPS‐indole ( 2 ) in the conformation with isopropyl groups ( g , g , g ).…”

The synthesis of chlorosilanes from alkoxysilanes, silanols, and hydrosilanes with bulky substituents

“…The reaction of alkyldimethylmethoxysilanes with concentrated hydrochloric acid also gave alkyldimethylchlorosilane in high yields. Thus, treatment of i-PrMe 2 SiOMe, sec-BuMe 2 SiOMe, cyclo-HexMe 2 SiOMe, and tert-BuMe 2 SiOMe with 35% aqueous HCl in hydrocarbon at 0°C produced the respective chlorosilanes in quantitative yields, as shown in Table 1 (run [11][12][13][14]. The structures of all chlorosilanes obtained in the present reactions were confirmed by mass and 1 H, 13 C, and 29 Si NMR spectrometric analysis, and spectral data for known compounds were identical with those of the authentic samples.…”

“…78-80°C/10 Torr). All spectral data obtained for i-Pr 3 SiCl are identical with those of the authentic sample reported previously [14].…”