Conformable and robust microfluidic force sensors to enable precision joint replacement surgery

Ives, Liam; Pace, Alizée; Bor, Fabian; Jing, Qingshen; Wade, Tom; Cama, Jehangir; Khanduja, Vikas; Kar‐Narayan, Sohini

doi:10.1016/j.matdes.2022.110747

Cited by 7 publications

(5 citation statements)

References 43 publications

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“…Although there are several reports about device ideas for instrumented prostheses for the hip [17, 20] and postoperative joint force measurements [2, 21], this is the first report of consecutive intraoperative soft tissue tension measurements during extension‐flexion movements. The lack of previous reports about such measurements, motivated us to provide context for the measured forces using a musculoskeletal computer model.…”

Section: Discussionmentioning

confidence: 99%

Soft‐tissue tension during total hip arthroplasty measured in four patients and predicted using a musculoskeletal model

Higa,

Tanino,

Ito

et al. 2023

J. exp. orthop.

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Purpose Soft-tissue tension around the hip joint is related to the incidence of dislocation after total hip arthroplasty (THA), but it remains difficult to quantify the soft-tissue tension during surgery. In this study, a three-dimensional force sensor-instrumented modular femoral head was developed and used to quantify soft-tissue tension during THA. The forces at the hip joint were also calculated using a three-dimensional musculoskeletal computer model to validate the measured forces. Methods Soft-tissue tension was investigated by measuring the hip joint forces and directions during intraoperative trialing in four patients through passive range of motion (ROM) from 0° extension to 90° flexion. A musculoskeletal model with THA, which was scaled to one of four patients, was developed. The hip joint forces were calculated under the same motion. Results Through the passive ROM, the magnitude of soft-tissue tension was greatest when the hip was extended, decreased with flexion to 34°, and progressively increased to flexion at 90°. The mediolateral force component was relatively constant, but the supero-inferior and anterior–posterior force components changed significantly. Within-individual variations were small during three repeated cycles of measurement, but magnitudes varied significantly among patients. Similar force patterns and magnitudes were calculated by the musculoskeletal model. Conclusions This study demonstrates that it is possible to quantify soft-tissue tension and direction during THA with an instrumented head. There was general agreement between the calculated and measured forces in both pattern and magnitude. Including additional subject-specific details would further enhance agreement between the model and measured hip forces.

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Section: Discussionmentioning

confidence: 99%

Soft‐tissue tension during total hip arthroplasty measured in four patients and predicted using a musculoskeletal model

Higa,

Tanino,

Ito

et al. 2023

J. exp. orthop.

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“…This capability in total hip replacement is a major unmet need. A microfluidic enabled bioelectronic pressure sensor has been developed to quantify force feedback within the hip joint, minimising implant failure 82 . When a force is applied to the fluid reservoir seen in Figure 2 The inlet is continuously perfused with an aqueous solution, small solutes then cross the semipermeable membrane by diffusion, the analyte of interest can now be measured at the outlet at regular intervals.…”

Section: Pressurementioning

confidence: 99%

“…A microfluidic enabled bioelectronic pressure sensor has been developed to quantify force feedback within the hip joint, minimising implant failure. 77 When a force is applied to the fluid reservoir seen in Fig. 2(c), the reservoir deforms and displaces the fluid along the channel.…”

Section: Sensingmentioning

confidence: 99%

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Fluidic enabled bioelectronic implants: opportunities and challenges

et al. 2022

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“…Implantable sensors for biomedical applications can provide an accurate and long-term solution to measurement and monitoring in comparison to multiple conventional invasive measurement procedures. Complications from total hip replacements can be monitored to reduce the impact on the patient, since wear, dislocation and impingement values are not being actively monitored [5].…”

Section: Introductionmentioning

confidence: 99%

Surface Acoustic Wave (SAW) Sensors for Hip Implant: A Numerical and Computational Feasibility Investigation Using Finite Element Methods

et al. 2023

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In this paper, a surface acoustic wave (SAW) sensor for hip implant geometry was proposed for the application of total hip replacement. A two-port SAW device was numerically investigated for implementation with an operating frequency of 872 MHz that can be used in more common radio frequency interrogator units. A finite element analysis of the device was developed for a lithium niobate (LiNBO3) substrate with a Rayleigh velocity of 3488 m/s on COMSOL Multiphysics. The Multiphysics loading and frequency results highlighted a good uniformity with numerical results. Afterwards, a hip implant geometry was developed. The SAW sensor was mounted at two locations on the implant corresponding to two regions along the shaft of the femur bone. Three discrete conditions were studied for the feasibility of the implant with upper- and lower-body loading. The loading simulations highlighted that the stresses experienced do not exceed the yield strengths. The voltage output results indicated that the SAW sensor can be implanted in the hip implant for hip implant-loosening detection applications.

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Conformable and robust microfluidic force sensors to enable precision joint replacement surgery

Cited by 7 publications

References 43 publications

Soft‐tissue tension during total hip arthroplasty measured in four patients and predicted using a musculoskeletal model

Soft‐tissue tension during total hip arthroplasty measured in four patients and predicted using a musculoskeletal model

Fluidic enabled bioelectronic implants: opportunities and challenges

Surface Acoustic Wave (SAW) Sensors for Hip Implant: A Numerical and Computational Feasibility Investigation Using Finite Element Methods

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