“…CLSM, a non-invasive diagnostic tool, was first reported in 1995 to be used in vivo on human tissue [8]. Since then, there has been many studies evaluating its role in viewing the microscopic features of normal skin [9] and various lesions such as cutaneous neoplasms [10,11], pigmented lesions [12,13,14], actinic keratosis [15], sebaceous gland hyperplasia [16], psoriasis [17], irritant and allergic contact dermatitis [18,19]. CLSM can distinguish melanocytes from other pigmented lesions like pigmented J Cancer Res Therap Oncol 2015 | Vol 3: 104 keratinocytes and melanophages [20].…”