Condyloma acuminatum: Epidemiological, clinical and therapeutic aspects

Abstract

Condyloma acuminatum, CA or genital warts, are benign fibro-epithelial tumors with a predilection for moist environments, especially mucosal surfaces. This sexually transmitted disease (STD) is increasing rapidly in incidence. The lesions are associated with a number of human papillomavirus (HPV) types. Some HPV types are closely linked with genital (especially cervical) dysplasia and neoplasia. Treatment consists of such traditional modalities as podophyllin, cryotherapy or surgical excision and, more recently, administration of interferon (IFN).

ZNT1 Regulates the Proliferation, Migration and Invasion of HaCaT Cells Infected with HPV Through the PI3K/Akt Pathway

“…CA, with high contagiousness, is a sexually transmitted disease caused by HPV infection. [ 19 ] Despite being a benign hyperplasia, CA has a high rate of recurrence and has the potential to grow into a malignant tumour or a larger CA, which has a major impact on the patients’ physical and mental health. [ 20 21 22 ] Abnormal proliferation of keratinocytes mediated by HPV has been reported to play an important role in the pathogenesis of CA.…”

Case Report: The Effect of 25% Podophyllin Tincture in Condylomata Accuminata

“…CA usually appear on the genitals as papules or cauliflower-like nodules in the vulva area, vaginal introitus, perianal, and cervix. Clinical manifestations are often found in women with a percentage of 38.6% compared to men [1]. Around 20 million people are infected each year, with an incidence rate of 6.2 million cases and more likely to increase.…”

Effectiveness of a combination therapy of traditional Chinese medicine and CO2 laser treatment for condyloma acuminatum

“…Condyloma acuminatum (CA) is a sexually transmitted disease caused by human papillomavirus infection, which primarily manifests as verrucous lesions. 1,2 The incidence of CA is 30 million cases per year worldwide and has been on the rise in recent times, on the basis of statistics from the World Health Organization. This disease is both highly infectious and frequently recurring and requires long-term, repeated treatments, which seriously affect the physical and psychological health of patients.…”

“…Condyloma acuminatum (CA) is a sexually transmitted disease caused by human papillomavirus infection, which primarily manifests as verrucous lesions 1,2 . The incidence of CA is 30 million cases per year worldwide and has been on the rise in recent times, on the basis of statistics from the World Health Organization.…”