Conductometric Study of Nimesulide in Aqueous Solutions of Hydrotropic Agents at Different Temperatures

Abstract

Conductance values of nimesulide have been determined in water in 0.1, 0.2, 0.4, 0.6, 0.8, 1 and 2 mol dm-3aqueous solutions of hydrotropic agents (sodium benzoate, sodium salicylate, sodium bromide and nicotinamide) at temperatures 298.15, 303.15, 308.15 and 313.15 K. The conductance values have been used to evaluate the limiting molar conductance and association constants by means of Shedlovsky extrapolation technique. Thermodynamic parameters for the association process of nimesulide in aqueous solutions of hydrotropic agents have also been calculated.

Albendazole Solubilization in Aqueous Solutions of Nicotinamide: Thermodynamics and Solute Solvent Interactions

“…It is well known that volumetric 3 and conductometric [16][17][18] studies of the solutions at definite and infinite dilution in a solvent system provide valuable information regarding the ion-ion and ionsolvent interactions. By examining the limiting apparent molar volume φ v 0 , limiting molar expansibility , limiting molar conductance (Λ 0 ) of solvent systems as a function of size, nature, temperature and composition of the solvent, it is possible to examine the parameters on solutesolvent interaction with the hope of obtaining a better understanding of interactions in solutions.…”

Conductometric studies of 1, 3, 5 –triazinothiocarbamide at different concentration and temperature

“…Conductometric studies of solutes at definite and infinite dilution in a solvent system provide valuable information regarding the ion-ion and ion-solvent interactions. By investigative the molar conductivity, association constants, Walden products of ionic solutions as a function of size, nature, temperature and composition of the solvent, it is possible to examine the parameters on solute-solvent interactions with the hope of obtaining a better understanding of interactions in solutions [8].…”

Solubility enhancement of simvastatin by arginine: thermodynamics, solute–solvent interactions, and spectral analysis

“…These parameters were used to discuss the solubility enhancement phenomenon; possible solute–solvent, solute–cosolute, and solvent–solvent interactions; the behavior of liquid systems; structure making and structure breaking phenomena; and related structural changes. 21 , 22 Further, these binary solution systems were analyzed using ultraviolet (UV)–visible spectrophotometer, Fourier-transform infrared (FTIR) spectroscopy, and 13 C, 1 H, and two-dimensional (2D) nuclear overhauser effect spectroscopy (NOESY) nuclear magnetic resonance (NMR) to complement thermophysical explanation.…”