Conductive diamond thin-films in electrochemistry

Hupert, Matt; Muck, Alexander; Wang, Jian; Stotter, Jason; Cvackova, Zuzana; Haymond, Shannon; Show, Yoshiyuki; Swain, Greg M.

doi:10.1016/s0925-9635(03)00260-7

Cited by 321 publications

(214 citation statements)

References 37 publications

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“…Diamond thin-film electrodes have been used as sensors in various applications of electroanalysis [1][2][3][4][5][6][7][8][9][10][11][12][13][14]. Synthesis of the polycrystalline film of diamond is carried out on the surface of a substrate in a close system.…”

Section: Introductionmentioning

confidence: 99%

Pulsed Amperometry for Anti-fouling of Boron-doped Diamond in Electroanalysis of β-Agonists: Application to Flow Injection for Pharmaceutical Analysis

Karuwan

Mantim

Chaisuwan

et al. 2006

Sensors

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This work presents the construction and application of boron-doped diamond (BDD) thin film electrode as sensor for the determination of three β-agonists, viz. salbutamol, terbutaline and clenbuterol. Although well-known as a chemically inert material, BDD film however shows fouling in detection of these compounds using fixedpotential mode amperometry. A suitable waveform for pulsed amperometric detection (PAD) was developed and used to determine the agonist compounds. It was seen that the developed PAD significantly refreshed the BDD surface for long-term detection in flow injection analysis. Linear working ranges were 0.5-100 µM, 1.0-100 µM and 0.5-50 µM for salbutamol, terbutaline and clenbuterol, respectively. The developed PAD-BDD system was applied to successfully determine salbutamol and terbutaline in commercial pharmaceutical products. The methods were validated with a capillary electrophoresis method.

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Section: Introductionmentioning

confidence: 99%

Pulsed Amperometry for Anti-fouling of Boron-doped Diamond in Electroanalysis of β-Agonists: Application to Flow Injection for Pharmaceutical Analysis

Karuwan

Mantim

Chaisuwan

et al. 2006

Sensors

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“…Recently, thin films of boron-doped diamond (BDD) emerged as a unique electrode material for several electrochemical applications, especially in electroanalysis. [26][27][28][29][30][31][32][33] BDD electrodes possess very attractive properties, which are significantly different from those of other conventional electrodes, e.g. glassy-carbon or platinum electrodes.…”

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confidence: 99%

Square-wave voltammetric determination of acetylsalicylic acid in pharmaceutical formulations using a boron-doped diamond electrode without the need of previous alkaline hydrolysis step

Sartori¹,

Medeiros²,

Rocha‐Filho³

et al. 2009

J. Braz. Chem. Soc.

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Neste trabalho descreve-se a determinação do ácido acetilsalicílico (ASA) em formulações farmacêuticas empregando voltametria de onda quadrada (SWV) e um eletrodo de diamante dopado com boro (BDD). Neste método, ASA é determinado diretamente em solução de H 2 SO 4 0,01 mol L -1 , sem a necessidade da hidrólise alcalina. Foi obtido um único pico de oxidação no potencial de 1,97 V vs. Ag/AgCl (KCl 3,0 mol L -1 ) com características de uma reação irreversível. A curva analítica obtida é linear na faixa de concentração ASA de 2,50 × 10 -6 -1,05 × 10 -4 mol L -1 , com um limite de detecção de 2,0 µmol L -1 . O desvio padrão relativo foi menor que 1,4% para uma solução de ASA 45 µmol L -1 (n = 10). O método proposto foi aplicado com sucesso para a determinação de ASA em várias formulações farmacêuticas e os resultados obtidos foram concordantes com um método oficial da Farmacopéia Britânica, a um nível de confiança de 95%.In this paper the determination of acetylsalicylic acid (ASA) in pharmaceutical formulations using square-wave voltammetry (SWV) and a boron-doped diamond electrode (BDD) is described. By this proposed method, ASA is directly determined in a 0.01 mol L -1 H 2 SO 4 solution without the need of a previous time-consuming alkaline hydrolysis step. A single oxidation peak at a potential of 1.97 V vs. Ag/AgCl (3.0 mol L -1 KCl) with the characteristics of an irreversible reaction was obtained. The obtained analytical curve is linear in the ASA concentration range 2.50 × 10 -6 -1.05 × 10 -4 mol L -1 , with a detection limit of 2.0 µmol L -1 . The obtained relative standard deviation was smaller than 1.4% for a 45 µmol L -1 ASA solution (n = 10). The proposed method was applied with success in the determination of ASA in several pharmaceutical formulations; the obtained results were in close agreement, at a 95% confidence level, with those obtained using an official method of the British Pharmacopoeia.Keywords: acetylsalicylic acid determination, boron-doped diamond electrode, square-wave voltammetry, pharmaceutical formulations IntroductionAcetylsalicylic acid (ASA), shown in Figure 1, more popularly known as aspirin, is one of the oldest medicines that still plays an important role in modern therapeutics. It is widely employed in pharmaceutical formulations for the relief of headaches, fever, muscular pain, and inflammation due to arthritis or injury. It was first synthesized in 1897, by Felix Hoffmann, in the Farbenfabrik Freidrich Bayer laboratories, in Elberfeld, Germany. 1,2 The high consumption of this substance all over the world 3,4 indicates the importance of the development of new analytical methods to assess not only the quality but also the authenticity of the product.The rate of decomposition of ASA to salicylic acid (SA) and acetic acid (AA) is dependent on solution pH and temperature. In the pH range 11-12 ASA is quickly hydrolyzed, in the pH range 4-8 its hydrolysis rate is slow, and maximum stability is attained at pH 2-3. 5 Commonly, ASA is indirectly determined after its conversion to SA ...

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“…The electrode charge transfer resistance is represented by the diameter of semicircle and is value 12.1 Ω. The double layer capacitance of diamond composite electrode was similar to that of boron doped diamond within 1 µF cm −2 which it is ten times lower than glassy carbon electrode capacitance [40,41]. the anodic oxidation of p-BQ was more active at medium solution.…”

Section: Electrode Characterizationmentioning

confidence: 97%

Enhanced performance based on a hybrid cathode backing layer using a biomass derived activated carbon framework for methanol fuel cells

Balakrishnan

İnal

Cooksey

et al. 2017

Electrochimica Acta

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Nano-diamond composite electrode was prepared and used as anode for anodic oxidation process for organic chemicals. Electrochemical techniques such as impedance and cyclic voltammetry have been used to characterize the diamond composite electrode properties.The oxidation power of the electrode was 0.8 V vs. Ag/AgCl, the charge transfer rate was 12.1 Ohm, and the double layer capacitance was less than 1 µF. The anodic oxidation behavior of p-benzoquinone, 2-chlorophenol, and phenol over diamond composite electrode were investigated by cyclic voltammetry in 0.1 M H2SO4 (pH 3) solution and 0.25 M Na2SO4 (pH 6.8) solution. Results marked that the electro-oxidation of pbenzoquinone was more active than phenol and 2-chlorophenol in the both solutions. Theperformance of the diamond composite electrode during incineration of 200 mg/L pbenzoquinone, 2-chlorophenol, phenol were investigated in an aqueous solution of pH 3 and pH 6.8 with 0.25 M Na2SO4 as the supporting electrolyte and applied current density of 40 mA/cm 2 . Results showed that the degradation rate of benzoquinone was faster than 2-chlorophenol and phenol in both different pH solutions. Moreover, the benzoquinone degradation rate was enhanced at high pH solution, on the contrary of that of 2-chlorophenol and phenol were clearly favored in acid medium.

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Conductive diamond thin-films in electrochemistry

Cited by 321 publications

References 37 publications

Pulsed Amperometry for Anti-fouling of Boron-doped Diamond in Electroanalysis of β-Agonists: Application to Flow Injection for Pharmaceutical Analysis

Pulsed Amperometry for Anti-fouling of Boron-doped Diamond in Electroanalysis of β-Agonists: Application to Flow Injection for Pharmaceutical Analysis

Square-wave voltammetric determination of acetylsalicylic acid in pharmaceutical formulations using a boron-doped diamond electrode without the need of previous alkaline hydrolysis step

Enhanced performance based on a hybrid cathode backing layer using a biomass derived activated carbon framework for methanol fuel cells

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