Conductimetric immunosensor based on poly(3,4-ethylenedioxythiophene)

Kanungo, Mandakini; Srivastava, Divesh N.; Kumar, Anil; Contractor, A.Q.

doi:10.1039/b111728a

Cited by 60 publications

(56 citation statements)

References 12 publications

(10 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Transistors have shown important applications in labelfree and high-sensitivity detection of biomolecules including antigen-antibody (Stern et al, 2007), DNA ), protein (Estrela et al, 2010Kanungo et al, 2002), enzyme (Yan et al, 2005), cells (Patolsky et al, 2006), etc. Organic electrochemical transistors (OECTs), as one type of OTFT, have attracted much attention in the past decades because the devices can be used in aqueous solutions with very stable performance and low operating voltages (∼1 V) (White et al, 1984;Bernards and Malliaras, 2007;Berggren and Richter-Dahlfors, 2007;Lin et al, 2010a).…”

Section: Introductionmentioning

confidence: 98%

Highly sensitive dopamine biosensors based on organic electrochemical transistors

Tang

Lin

Chan

et al. 2011

Biosensors and Bioelectronics

211

174

View full text Add to dashboard Cite

Organic electrochemical transistors (OECTs) based on poly(3,4-ethylenedioxythiophene):poly(styrene sulfonic acid) (PEDOT:PSS) with different gate electrodes, including graphite, Au and Pt electrode, etc., have been used as dopamine sensor for the first time. The sensitivity of the OECT to dopamine depends on its gate electrode and operation voltage. We find that the device with a Pt gate electrode characterized at the gate voltage of 0.6 V shows the highest sensitivity. The detection limit of the device to dopamine is lower than 5 nM, which is one order of magnitude better than a conventional electrochemical measurement with the same Pt electrode. It is expected that OECT is a good candidate for low cost and highly sensitive biosensor for the detection of dopamine.

show abstract

Section: Introductionmentioning

confidence: 98%

Highly sensitive dopamine biosensors based on organic electrochemical transistors

Tang

Lin

Chan

et al. 2011

Biosensors and Bioelectronics

211

174

View full text Add to dashboard Cite

show abstract

“…[14] A key aspect in most sensing applications based on OECTs is to optimize the gate capacitance in relation to the channel capacitance in order to achieve maximum sensitivity. [15] To date, PEDOT:PSS-based OECTs have been used in a plethora of applications, including enzymatic sensing [11], DNA detection [16], sensing of antibodies [17] and studies of cell layer formation [18]. Within neuroscience it has been shown that PEDOT:PSS coatings can improve the recording capabilities of neural electrodes and recently PEDOT:PSS-based OECTs were used to improve neuronal signal recordings by amplification of the signal on-site.…”

Section: Introductionmentioning

confidence: 99%

Organic electrochemical transistors for signal amplification in fast scan cyclic voltammetry

Tybrandt

Kollipara

Berggren

2014

Sensors and Actuators B: Chemical

View full text Add to dashboard Cite

Fast scan cyclic voltammetry (FSCV) is an electrochemical method commonly used in neuroscience for spatiotemporal measurement of the concentration of dopamine and other electroactive species. Since FSCV involves wide bandwidth measurements of low currents, the technique is normally very sensitive to electrical noise and is typically performed inside a Faraday cage. In order to reduce the electrical noise and to enable measurements in an unshielded environment, we take use of

show abstract

“…An emerging focus in the field involves the use of organic-based devices as transducers in chemical and biological sensors [64][65][66] . Early OECT fabrication used varying types of conducting polymers, for example: polyaniline [67,68] , polycarbazole [69] , polythiophene, and their derivatives [70,71] . However limitations were also faced when using these devices as biosensors.…”

Section: Electrochemical Biosensing: Organic Electrochemical Transistmentioning

confidence: 99%

Wearable electrochemical sensors for monitoring performance athletes

Fraser¹,

Curto²,

Coyle³

et al. 2011

SPIE Proceedings

View full text Add to dashboard Cite

Nowadays, wearable sensors such as heart rate monitors and pedometers are in common use. The use of wearable systems such as these for personalized exercise regimes for health and rehabilitation is particularly interesting. In particular, the true potential of wearable chemical sensors, which for the real-time ambulatory monitoring of bodily fluids such as tears, sweat, urine and blood has not been realized. Here we present a brief introduction into the fields of ionogels and organic electrochemical transistors, and in particular, the concept of an OECT transistor incorporated into a sticking-plaster, along with a printable "ionogel" to provide a wearable biosensor platform.

show abstract

Conductimetric immunosensor based on poly(3,4-ethylenedioxythiophene)

Abstract: A conductimetric reagentless immunosensor using the biospecific binding pair of goat antirabbit IgG and rabbit IgG has been designed and fabricated using poly (3,4-ethylenedioxythiophene) as the immobilization matrix-cumtransducer.

Cited by 60 publications

References 12 publications

Highly sensitive dopamine biosensors based on organic electrochemical transistors

Highly sensitive dopamine biosensors based on organic electrochemical transistors

Organic electrochemical transistors for signal amplification in fast scan cyclic voltammetry

Wearable electrochemical sensors for monitoring performance athletes

Contact Info

Product

Resources

About