We examined drug-scene familiarity and exposure to gang violence among residents of a migrant farming community in rural Baja California, Mexico. In October 2010, 164 members of a single colonia (community) underwent an interviewer-administered survey to assess ‘exposure to gang violence’ and ‘drug-scene familiarity’, as well as other health indicators. Logistic regression was used to identify correlates of exposure to gang violence. Overall, 20% of participants were male, the median age was 27 years, 24% spoke an indigenous language, 42% reported exposure to gang violence, and 39% reported drug-scene familiarity. Factors independently associated with exposure to gang violence included being younger (AOR=0.80 per 5-year increase, 95% CI=0.67–0.96), living in the community longer (AOR=1.47 per 5-year increase, 95% CI=1.11–1.72), higher educational attainment (AOR=1.70 per 5-year increase, 95% CI=1.07–1.12), and drug-scene familiarity (AOR=5.10, 95%CI=2.39–10.89). Exposure to gang violence was very common in this community and was associated with drug-scene familiarity, suggesting a close relationship between drugs and gang violence in this rural community. In a region characterised by mass migration from poorer parts of Mexico, where drugs and gangs have not been previously reported, emerging social harms may affect these communities unless interventions are implemented.