Conditioned-medium of stem cells from human exfoliated deciduous teeth prevent apoptosis of neural progenitors

Zainuri, Masagus; Purba, Jan S.; Jusman, Sri WA; Bachtiar, Endang Winiati

doi:10.1016/j.sdentj.2022.08.005

Cited by 2 publications

(2 citation statements)

References 29 publications

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“…Some studies have reported that SHEDs can not only alleviate trigeminal neuralgia by inhibiting endoplasmic reticulum stress but also prevent apoptosis of neural progenitor cells to a certain extent and promote facial nerve regeneration. 59,60 Although the proliferation and differentiation of SHEDs share similarities with many odontogenic MSCs, their natural shedding and non-invasive acquisition add new possibilities for stem cell applications, and storing SHEDs when children shed their milk teeth may be beneficial in treating future injuries or diseases. 59,[61][62][63][64][65]…”

Section: Shedmentioning

confidence: 99%

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Nanomaterials Modulating the Fate of Dental-Derived Mesenchymal Stem Cells Involved in Oral Tissue Reconstruction: A Systematic Review

Li,

Wang,

Huang

et al. 2023

IJN

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The critical challenges in repairing oral soft and hard tissue defects are infection control and the recovery of functions. Compared to conventional tissue regeneration methods, nano-bioactive materials have become the optimal materials with excellent physicochemical properties and biocompatibility. Dental-derived mesenchymal stem cells (DMSCs) are a particular type of mesenchymal stromal cells (MSCs) with great potential in tissue regeneration and differentiation. This paper presents a review of the application of various nano-bioactive materials for the induction of differentiation of DMSCs in oral and maxillofacial restorations in recent years, outlining the characteristics of DMSCs, detailing the biological regulatory effects of various nano-materials on stem cells and summarizing the material-induced differentiation of DMSCs into multiple types of tissue-induced regeneration strategies. Nanomaterials are different and complementary to each other. These studies are helpful for the development of new nanoscientific research technology and the clinical transformation of tissue reconstruction technology and provide a theoretical basis for the application of nanomaterial-modified dental implants. We extensively searched for papers related to tissue engineering bioactive constructs based on MSCs and nanomaterials in the databases of PubMed, Medline, and Google Scholar, using keywords such as "mesenchymal stem cells", "nanotechnology", "biomaterials", "dentistry" and "tissue regeneration". From 2013 to 2023, we selected approximately 150 articles that align with our philosophy.

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Section: Shedmentioning

confidence: 99%

“…59,60 Although the proliferation and differentiation of SHEDs share similarities with many odontogenic MSCs, their natural shedding and non-invasive acquisition add new possibilities for stem cell applications, and storing SHEDs when children shed their milk teeth may be beneficial in treating future injuries or diseases. 59,[61][62][63][64][65]…”

Section: Shedmentioning

confidence: 99%