Condition of Cellular and Humoral Relationships of Immunity in Candida Associated Parodontitis With Medium and High Degree of Quantitative Replacement of Paradontal Pockets

Мирсаева, Ф. З.; Mirsaeva, Faniya; Ханов, Тимур; Hanov, Timur

doi:10.18481/2077-7566-2019-15-2-122-127

Cited by 3 publications

(1 citation statement)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Пародонтити характеризуються тяжкими наслідками, які призводять до порушення зубощелепної системи [16,18], змін в імунному статусі хворих, що призводить до зниження реактивності організму [19].…”

unclassified

The Incidence of the Population of Ukraine of Inflammatory Periodontal Diseases, Prediction and Prevention of Pathology in Modern Conditions

Зюзін¹,

Черно²,

Cherno³

et al. 2021

Ukr. ž. med. bìol. sportu

View full text Add to dashboard Cite

The purpose of the study. The article reflects the issues of the incidence of inflammatory periodontal diseases in the population of Ukraine, methods for predicting exacerbations of diseases for the timely conduct of secondary prevention. It has been established that the high prevalence of periodontal diseases among different groups of the population makes this problem one of the most important problems of modern dentistry. According to WHO experts, 80% of schoolchildren in different countries have periodontal pathology, and among adults it occurs in almost 100% of cases. Modern periodontal prophylaxis should be carried out on the basis of clinical examination of patients. Periodontal prophylaxis should be based on taking into account the identified etiological factors of the disease. Predicting the incidence of periodontitis and predicting the course of the disease is one of the most important problems of periodontology today. Solving forecasting problems in clinical, experimental and preventive medicine is one of the most difficult areas of the activity of doctors of various profiles. Materials and methods. In order to form a risk group, the occurrence of an exacerbation of inflammatory periodontal diseases for the timely implementation of secondary prevention of pathology, an algorithm for the probability of diseases and a mathematical model for predicting the course of the disease were developed. The use of this method made it possible to select 9 signs out of 42 that most significantly affect the prognosis of exacerbation in inflammatory periodontal diseases. Results and discussion. Based on the curves of the dependence of the frequency of the occurrence of exacerbation of inflammatory periodontal diseases on the magnitude of the risk of exacerbation of this pathology, 3 degrees of prognosis probability were determined: low, medium, high. The use of the method of stepwise discriminant analysis made it possible to develop a system for predicting the possibility of an exacerbation of inflammatory periodontal disease and to scientifically substantiate the principles of identifying risk groups for the possibility of exacerbation of inflammatory periodontal diseases in this group of examination. For patients with a risk of exacerbation, dynamic observation was established for one year, before the beginning of which they were divided into 2 groups – the study and control. Patients in the study group underwent preventive treatment, which included the appointment of an appropriate diet, work and rest regimen, correction of the state of the immune system using immunomodulatory drugs, treatment of concomitant diseases and local treatment of inflammatory periodontal diseases. Patients in the control group underwent conventional prophylaxis, which included adherence to general rules: a rational regimen, a balanced diet, rational oral hygiene, and basic sanitary and educational work. Conclusion. As shown by the results of dynamic observation, among patients of the study group, exacerbation of the disease was observed in 14.3% of cases, in patients of the control group – in 42.5%, which corresponded to the likelihood of an exacerbation of the disease by 94.5%

show abstract

unclassified

The Incidence of the Population of Ukraine of Inflammatory Periodontal Diseases, Prediction and Prevention of Pathology in Modern Conditions

Зюзін¹,

Черно²,

Cherno³

et al. 2021

Ukr. ž. med. bìol. sportu

View full text Add to dashboard Cite

show abstract

Evaluation of the Clinical Effectiveness of Toothpaste Containing Grapefruit Extract and Lysotech and Protelyse Lysates in the Complex Treatment of Inflammatory Periodontal Diseases

Токмакова

Бондаренко

Lunitsyna

2021

Actual Problems in Dentistry

View full text Add to dashboard Cite

The preventive direction in dentistry is the leading one today. Individual oral hygiene plays a significant role in preventing the development of inflammatory periodontal diseases. The use of therapeutic and prophylactic toothpastes containing natural components with antibacterial properties is promising. Among plant extracts, grapefruit extract has the most pronounced antimicrobial activity. LysoTech and ProteLyse lysates, which have antimicrobial and immunomodulatory effects, have long been used in dentistry in the form of tablets for resorption in the complex treatment of various diseases. Their introduction into toothpastes is also considered a promising direction for the prevention and treatment of oral pathology. The aim of our study was to clinically evaluate the effectiveness of therapeutic and prophylactic toothpaste, which contains grapefruit extract and LysoTech and ProteLyse lysates, in patients with inflammatory diseases of periodontal tissues. A clinical and laboratory comparative study of two therapeutic and prophylactic toothpastes was conducted. The composition of the samples was identical, except for two components: grapefruit extract and LysoTech and ProteLyse lysates. The study involved 60 volunteers who were divided into two groups depending on the toothpastes used. The purifying and anti-inflammatory effects of the samples were evaluated for one month. An in vitro laboratory study was also conducted to identify the antimicrobial properties of toothpastes. During the work, high clinical results were noted in a group of volunteers using toothpaste with grapefruit seed extract and bacterial lysates, which are expressed in a decrease in PMA and SBI indices, and an improvement in oral hygiene. According to a laboratory study, the toothpaste containing grapefruit extract and LysoTech and ProteLyse lysates has a more pronounced antimicrobial and antifungal effect, which indicates a high preventive and therapeutic potential of the test sample.

show abstract

Analysis of the Incidence of Prostate Cancer and the State of the Organization of Oncological Care for Patients in Ukraine

Зюзін¹,

Saveliev²,

Tuzova³

et al. 2022

Ukr. ž. med. bìol. sportu

View full text Add to dashboard Cite

The purpose of the study was to highlight the incidence of prostate cancer and the state of the organization of oncological care for patients in Ukraine. Materials and methods. Monitoring of the defeat of the population of Ukraine by malignant neoplasms, which is carried out by the network of the National Cancer Registry, allows to obtain reliable information about the features of the development of this process. To determine the priorities in the organization of patients with cancer, a study of the onco-epidemiological situation and the state of organization of oncological care for patients with malignant neoplasms was carried out. Results and discussion. Coming out of the realities that are caused by the coronovirus pandemic, special attention was paid not only to the general level of prostate cancer in Ukraine, but also to the structural age-related features of cancer incidence and mortality. The most pronounced changes relate to the structural features of the incidence of malignant neoplasms of the prostate gland, the proportion of which in the structure of the incidence of the male population has been constantly increasing over the past years. In the structure of mortality from cancer of the male population, an increase in the proportion of malignant neoplasms of the prostate gland should also be noted. Prostate cancer is characterized by the highest annual increase in incidence per 100,000 male population. The morbidity rate reaches its maximum values in the age groups of 70–74 and 80–84 years old, mortality – in groups of 80–84 years old. Starting from the age category of 50–54 years to the age of 70–74 years, in each older group, the incidence rate increases by 2–3 times and decreases only at the age of more than 85 years. Conclusion. As a result, this pathology takes the second place in the structure of the incidence of the male population aged 55–74 years and the first place in the age group of more than 75 years. Diagnostic and therapeutic care for patients with prostate cancer is characterized by a high level of neglect and mortality from cancer. Not in all cases, morphological verification is carried out; the stage of the malignant neoplasm is not always determined. As a result of such negligence, the long-term results of treatment in Ukraine are much worse than in Europe and the USA. The experience of economically developed countries shows that with a clear organization of the treatment and diagnostic process, significant success can be achieved in providing oncological care to the population

show abstract

Condition of Cellular and Humoral Relationships of Immunity in Candida Associated Parodontitis With Medium and High Degree of Quantitative Replacement of Paradontal Pockets

Cited by 3 publications

References 4 publications

The Incidence of the Population of Ukraine of Inflammatory Periodontal Diseases, Prediction and Prevention of Pathology in Modern Conditions

The Incidence of the Population of Ukraine of Inflammatory Periodontal Diseases, Prediction and Prevention of Pathology in Modern Conditions

Evaluation of the Clinical Effectiveness of Toothpaste Containing Grapefruit Extract and Lysotech and Protelyse Lysates in the Complex Treatment of Inflammatory Periodontal Diseases

Analysis of the Incidence of Prostate Cancer and the State of the Organization of Oncological Care for Patients in Ukraine

Contact Info

Product

Resources

About